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AJP in Advance articles have been peer reviewed, copyedited, and approved by authors but have not yet appeared in the print journal. Publication ahead of print allows articles to become available in a rapid and timely manner. Articles in AJP in Advance may be cited using the date they were posted online and their unique digital object identifier (DOI).

ARTICLE
The Separation Anxiety Hypothesis of Panic Disorder Revisited: A Meta-Analysis Joe Kossowsky, Monique C. Pfaltz, Silvia Schneider, Jan Taeymans, Cosima Locher, Jens Gaab
ARTICLE
Antidepressant Medication Augmented With Cognitive-Behavioral Therapy for Generalized Anxiety Disorder in Older Adults Julie Loebach Wetherell, Andrew J. Petkus, Kamila S. White, Hoang Nguyen, Sander Kornblith, Carmen Andreescu, Sidney Zisook, Eric J. Lenze
ARTICLE
Psychodynamic Therapy and Cognitive-Behavioral Therapy in Social Anxiety Disorder: A Multicenter Randomized Controlled Trial Falk Leichsenring, Simone Salzer, Manfred E. Beutel, Stephan Herpertz, Wolfgang Hiller, Juergen Hoyer, Johannes Huesing, Peter Joraschky, Bjoern Nolting, Karin Poehlmann, Viktoria Ritter, Ulrich Stangier, Bernhard Strauss, Nina Stuhldreher, Susan Tefikow, Tobias Teismann, Ulrike Willutzki, Joerg Wiltink, Eric Leibing
ARTICLE
Alterations in Brain Structures Related to Taste Reward Circuitry in Ill and Recovered Anorexia Nervosa and in Bulimia Nervosa Guido K. Frank, Megan E. Shott, Jennifer O. Hagman, Vijay A. Mittal
EDITORIAL
The Gordian Knot of Clinical Research in Anxiety Disorders: Some Answers, More Questions Barbara Milrod
EDITORIAL
What Are the Optimal Treatment Courses for Geriatric Anxiety, and How Do We Find Out? David H. Barlow, Jonathan S. Comer
ARTICLE
Evaluation of the FDA Warning Against Prescribing Citalopram at Doses Exceeding 40 mg Kara Zivin, Paul N. Pfeiffer, Amy S.B. Bohnert, Dara Ganoczy, Frederic C. Blow, Brahmajee K. Nallamothu, Helen C. Kales
ARTICLE
Psychotic Experiences and Psychotic Disorders at Age 18 in Relation to Psychotic Experiences at Age 12 in a Longitudinal Population-Based Cohort Study Stanley Zammit, Daphne Kounali, Mary Cannon, Anthony S. David, David Gunnell, Jon Heron, Peter B. Jones, Shôn Lewis, Sarah Sullivan, Dieter Wolke, Glyn Lewis
REVIEWS AND OVERVIEWS
“Selfish Spermatogonial Selection”: A Novel Mechanism for the Association Between Advanced Paternal Age and Neurodevelopmental Disorders Anne Goriely, John J. McGrath, Christina M. Hultman, Andrew O.M. Wilkie, Dolores Malaspina
ARTICLE
Adapting Smoking Cessation Treatment According to Initial Response to Precessation Nicotine Patch Jed E. Rose, Frédérique M. Behm
COMMENTARY
China’s New Mental Health Law: Reframing Involuntary Treatment Michael R. Phillips, Hanhui Chen, Kate Diesfeld, Bin Xie, Hui G. Cheng, Graham Mellsop, Xiehe Liu
ARTICLE
Association of GSK-3β Genetic Variation With GSK-3β Expression, Prefrontal Cortical Thickness, Prefrontal Physiology, and Schizophrenia Giuseppe Blasi, Francesco Napolitano, Gianluca Ursini, Annabella Di Giorgio, Grazia Caforio, Paolo Taurisano, Leonardo Fazio, Barbara Gelao, Maria Teresa Attrotto, Lucia Colagiorgio, Giovanna Todarello, Francesco Piva, Apostolos Papazacharias, Rita Masellis, Marina Mancini, Annamaria Porcelli, Raffaella Romano, Antonio Rampino, Tiziana Quarto, Matteo Giulietti, Barbara K. Lipska, Joel E. Kleinman, Teresa Popolizio, Daniel R. Weinberger, Alessandro Usiello, Alessandro Bertolino
ARTICLE
Moderators of Outcome in Late-Life Depression: A Patient-Level Meta-Analysis J. Craig Nelson, Kevin L. Delucchi, Lon S. Schneider
ARTICLE
Childhood Trauma and Psychosis in a Prospective Cohort Study: Cause, Effect, and Directionality Ian Kelleher, Helen Keeley, Paul Corcoran, Hugh Ramsay, Camilla Wasserman, Vladimir Carli, Marco Sarchiapone, Christina Hoven, Danuta Wasserman, Mary Cannon
ARTICLE
d-Cycloserine as an Augmentation Strategy With Cognitive-Behavioral Therapy for Social Anxiety Disorder Stefan G. Hofmann, Jasper A.J. Smits, David Rosenfield, Naomi Simon, Michael W. Otto, Alicia E. Meuret, Luana Marques, Angela Fang, Candyce Tart, Mark H. Pollack
ARTICLE
High Loading of Polygenic Risk for ADHD in Children With Comorbid Aggression Marian L. Hamshere, Kate Langley, Joanna Martin, Sharifah Shameem Agha, Evangelia Stergiakouli, Richard J.L. Anney, Jan Buitelaar, Stephen V. Faraone, Klaus-Peter Lesch, Benjamin M. Neale, Barbara Franke, Edmund Sonuga-Barke, Philip Asherson, Andrew Merwood, Jonna Kuntsi, Sarah E. Medland, Stephan Ripke, Hans-Christoph Steinhausen, Christine Freitag, Andreas Reif, Tobias J. Renner, Marcel Romanos, Jasmin Romanos, Andreas Warnke, Jobst Meyer, Haukur Palmason, Alejandro Arias Vasquez, Nanda Lambregts-Rommelse, Herbert Roeyers, Joseph Biederman, Alysa E. Doyle, Hakon Hakonarson, Aribert Rothenberger, Tobias Banaschewski, Robert D. Oades, James J. McGough, Lindsey Kent, Nigel Williams, Michael J. Owen, Peter Holmans, Michael C. O’Donovan, Anita Thapar
ARTICLE
Increase in Work Productivity of Depressed Individuals With Improvement in Depressive Symptom Severity Madhukar H. Trivedi, David W. Morris, Stephen R. Wisniewski, Ira Lesser, Andrew A. Nierenberg, Ella Daly, Benji T. Kurian, Bradley N. Gaynes, G.K. Balasubramani, A. John Rush
ARTICLE
Relapse Duration, Treatment Intensity, and Brain Tissue Loss in Schizophrenia: A Prospective Longitudinal MRI Study Nancy C. Andreasen, Dawei Liu, Steven Ziebell, Anvi Vora, Beng-Choon Ho
ARTICLE
Cognitive Experiences Reported by Patients With Borderline Personality Disorder and Axis II Comparison Subjects: A 16-Year Prospective Follow-Up Study Mary C. Zanarini, Frances R. Frankenburg, Michelle M. Wedig, Garrett M. Fitzmaurice
ARTICLE
White Matter Microstructure and Atypical Visual Orienting in 7-Month-Olds at Risk for Autism Jed T. Elison, Sarah J. Paterson, Jason J. Wolff, J. Steven Reznick, Noah J. Sasson, Hongbin Gu, Kelly N. Botteron, Stephen R. Dager, Annette M. Estes, Alan C. Evans, Guido Gerig, Heather C. Hazlett, Robert T. Schultz, Martin Styner, Lonnie Zwaigenbaum, Joseph Piven,
ARTICLE
Transitions in Illicit Drug Use Status Over 3 Years: A Prospective Analysis of a General Population Sample Wilson M. Compton, Deborah A. Dawson, Kevin P. Conway, Marc Brodsky, Bridget F. Grant
ARTICLE
Efficacy of Functional Remediation in Bipolar Disorder: A Multicenter Randomized Controlled Study Carla Torrent, Caterina del Mar Bonnin, Anabel Martínez-Arán, Jesús Valle, Benedikt L. Amann, Ana González-Pinto, José Manuel Crespo, Ángela Ibáñez, Mari Paz Garcia-Portilla, Rafael Tabarés-Seisdedos, Celso Arango, Francesc Colom, Brisa Solé, Isabella Pacchiarotti, Adriane R. Rosa, Jose Luis Ayuso-Mateos, Celia Anaya, Patricia Fernández, Ramon Landín-Romero, Silvia Alonso-Lana, Jordi Ortiz-Gil, Bárbara Segura, Sara Barbeito, Patricia Vega, Miryam Fernández, Amaia Ugarte, Marta Subirà, Ester Cerrillo, Núria Custal, José Manuel Menchón, Jerónimo Saiz-Ruiz, Jose Maria Rodao, Sandra Isella, Analucía Alegría, Susana Al-Halabi, Julio Bobes, Gonzalo Galván, Pilar A. Saiz, Vicent Balanzá-Martínez, Gabriel Selva, Inmaculada Fuentes-Durá, Patricia Correa, María Mayoral, Guadalupe Chiclana, Jessica Merchan-Naranjo, Marta Rapado-Castro, Manel Salamero, Eduard Vieta
REVIEWS AND OVERVIEWS
A Model of Placebo Response in Antidepressant Clinical Trials Bret R. Rutherford, Steven P. Roose