Skip to main content
No access
Article
Published Online: January 1946

CONVULSIVE STATES AND COMA IN CASES OF ISLET CELL ADENOMA OF THE PANCREAS

Publication: American Journal of Psychiatry

Abstract

This report is an analysis of neurological and psychiatric manifestations observed in 27 patients suffering from verified adenoma of the islet cell apparatus of the pancreas. In addition relevant laboratory data, mainly those related to the glucose metabolism and in the last 11 patients also the EEG findings are discussed.
The clinical data were arranged in four groups: (1) autonomic-visceral, (2)somatic-neurological, (3) "psychomotor" manifestations and (4) seizures and seizure fragments.
These four groups of data are then discussed in terms of anatomic-physiological levels using concepts established by Himwich. Our findings differ in several important aspects from those found in therapeutic insulin shock. An attempt is made to understand the reasons for this divergence.
Glucose tolerance curves in a majority of our cases are diabetic in pattern and often also in level. "Flat" curves are the exception in our experience.
The EEG findings are those to be expected in patients whose cerebral metabolism is depressed. In addition suggestive "convulsive" patterns such as spike-and-wave bursts are found in most of our patients, even those who had no clinical convulsive seizures.

Get full access to this article

View all available purchase options and get full access to this article.

Information & Authors

Information

Published In

Go to American Journal of Psychiatry
Go to American Journal of Psychiatry
American Journal of Psychiatry
Pages: 486 - 495
PubMed: 21016895

History

Published in print: January 1946
Published online: 1 April 2006

Authors

Details

PAUL F. A. HOEFER
The Department of Neurology, Columbia University, College of Physicians and Surgeons, and the Neurological Institute of New York.
SAMUEL A. GUTTMAN
The Department of Neurology, Columbia University, College of Physicians and Surgeons, and the Neurological Institute of New York.
IRVING J. SANDS
The Department of Neurology, Columbia University, College of Physicians and Surgeons, and the Neurological Institute of New York.

Metrics & Citations

Metrics

Citations

Export Citations

If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click Download.

For more information or tips please see 'Downloading to a citation manager' in the Help menu.

Format
Citation style
Style
Copy to clipboard

View Options

Get Access

Login options

Already a subscriber? Access your subscription through your login credentials or your institution for full access to this article.

Personal login Institutional Login Open Athens login
Purchase Options

Purchase this article to access the full text.

PPV Articles - American Journal of Psychiatry

PPV Articles - American Journal of Psychiatry

Not a subscriber?

Subscribe Now / Learn More

PsychiatryOnline subscription options offer access to the DSM-5-TR® library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development.

Need more help? PsychiatryOnline Customer Service may be reached by emailing [email protected] or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.).

View options

PDF/ePub

View PDF/ePub

Media

Figures

Other

Tables

Share

Share

Share article link

Share