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Published Online:https://doi.org/10.1176/ajp.125.5.593

After reviewing various strategies of drug appraisal, the authors suggest a psychodynamic approach to the assessment of psychotropic drugs. They present ten ego functions and their component factors, as well as examples of how the functions are assessed from interviews, clinical psychological tests, and psychological laboratory procedures. Suggestions are offered for the use of these ego function measures in drug evaluation research.

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