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Published Online: 1 January 2014

Neuropsychological Outcomes After Psychosocial Intervention for Depression in Parkinson’s Disease

Roseanne D. Dobkin, Ph.D., Alexander I. Tröster, Ph.D., Jade Tiu Rubino, Psy.D., Lesley A. Allen, Ph.D., Michael A. Gara, Ph.D., Margery H. Mark, M.D., and Matthew Menza, M.D.Authors Info & Affiliations

Publication: The Journal of Neuropsychiatry and Clinical Neurosciences

Volume 26, Number 1

https://doi.org/10.1176/appi.neuropsych.12120381

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Abstract

The authors describe neuropsychological outcomes in people with Parkinson’s disease after their participation in an NIH-sponsored, randomized controlled trial of cognitive-behavioral treatment for depression. Improvements in mood were associated with modest gains in verbal memory and executive functioning over the 10-week treatment period.

Abstract

The authors describe neuropsychological outcomes in people with Parkinson’s disease (PD) after their participation in an NIH-sponsored, randomized, controlled trial of cognitive-behavioral treatment for depression. Improvements in mood were associated with modest gains in verbal memory and executive functioning over the 10-week treatment period and accounted for greater variance in neuropsychological outcomes at the end of treatment than other known correlates of cognitive functioning in PD, such as disease severity, age, and education. Baseline working memory and executive skills were also associated with depression improvement over time.

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Information & Authors

Information

Published In

Go to The Journal of Neuropsychiatry and Clinical Neurosciences

Go to The Journal of Neuropsychiatry and Clinical Neurosciences

The Journal of Neuropsychiatry and Clinical Neurosciences

Volume 26 • Number 1 • Winter 2014

Pages: 57 - 63

PubMed: 24275895

History

Received: 3 December 2012

Accepted: 1 February 2013

Published online: 1 January 2014

Published in print: Winter 2014

Authors

Details

Roseanne D. Dobkin, Ph.D.

From the Depts. of Psychiatry and Neurology, Robert Wood Johnson Medical School, University of Medicine & Dentistry of New Jersey, and the Barrow Neurological Institute, Arizona (AIT).

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Alexander I. Tröster, Ph.D.

From the Depts. of Psychiatry and Neurology, Robert Wood Johnson Medical School, University of Medicine & Dentistry of New Jersey, and the Barrow Neurological Institute, Arizona (AIT).

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Jade Tiu Rubino, Psy.D.

From the Depts. of Psychiatry and Neurology, Robert Wood Johnson Medical School, University of Medicine & Dentistry of New Jersey, and the Barrow Neurological Institute, Arizona (AIT).

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Lesley A. Allen, Ph.D.

From the Depts. of Psychiatry and Neurology, Robert Wood Johnson Medical School, University of Medicine & Dentistry of New Jersey, and the Barrow Neurological Institute, Arizona (AIT).

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Michael A. Gara, Ph.D.

From the Depts. of Psychiatry and Neurology, Robert Wood Johnson Medical School, University of Medicine & Dentistry of New Jersey, and the Barrow Neurological Institute, Arizona (AIT).

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Margery H. Mark, M.D.

From the Depts. of Psychiatry and Neurology, Robert Wood Johnson Medical School, University of Medicine & Dentistry of New Jersey, and the Barrow Neurological Institute, Arizona (AIT).

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Matthew Menza, M.D.

From the Depts. of Psychiatry and Neurology, Robert Wood Johnson Medical School, University of Medicine & Dentistry of New Jersey, and the Barrow Neurological Institute, Arizona (AIT).

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Notes

Send correspondence to Dr. Dobkin; e-mail: [email protected]

Funding Information

This study was funded by 1 K23 NS052155-01A2 awarded to Roseanne D. Dobkin by the National Institute of Neurological Disorders and Stroke (NIH/NINDS). This trial is registered at clinicaltrials.gov: Identifier NCT00464464.

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