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Abstract

Objective:

Relapse and its predictors were examined among patients with schizophrenia in the year after hospital discharge.

Methods:

The sample included 200 patients with schizophrenia participating in a German multicenter study. Relapse was defined as a worsening of psychopathological symptoms or rehospitalization in the year after hospital discharge. Predictors examined were variables related to course of illness and to response and remission at discharge.

Results:

Fifty-two percent of participants had a relapse. Patients whose symptoms were not in remission at discharge were more likely to have a relapse, as were those who had more severe symptoms and more side effects at discharge. Those who experienced a relapse were less likely to be taking a second-generation antipsychotic at discharge, less likely to have a positive attitude toward treatment adherence, and less likely to be employed.

Conclusions:

The high rate of relapse among patients with schizophrenia highlights the need to improve current treatment strategies. (Psychiatric Services 63:87–90, 2012)

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Figure 1 Relapse during the year after hospital discharge among 200 patients, by whether their symptoms had responded to treatment or were in remission at discharge

Information & Authors

Information

Published In

Go to Psychiatric Services
Go to Psychiatric Services
Cover: Mount Vesuvius, by Andy Warhol, 1985. Museo Nazionale di Capodimonte, Naples, Italy. © The Andy Warhol Foundation for the Visual Arts, Inc/Artists Rights Society, New York.
Psychiatric Services
Pages: 87 - 90
PubMed: 22227766

History

Published online: 1 January 2012
Published in print: January 2012

Authors

Details

Rebecca Schennach, M.D. [email protected]
Dr. Schennach, Mr. Obermeier, Mr. Meyer, Prof. Jäger, Dr. Seemüller, Prof. Möller, and Prof. Riedel are affiliated with the Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University, Nussbaumstreet 7, 80336 Munich, Germany (e-mail: [email protected]).
Michael Obermeier [email protected]
Dr. Schennach, Mr. Obermeier, Mr. Meyer, Prof. Jäger, Dr. Seemüller, Prof. Möller, and Prof. Riedel are affiliated with the Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University, Nussbaumstreet 7, 80336 Munich, Germany (e-mail: [email protected]).
Sebastian Meyer [email protected]
Dr. Schennach, Mr. Obermeier, Mr. Meyer, Prof. Jäger, Dr. Seemüller, Prof. Möller, and Prof. Riedel are affiliated with the Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University, Nussbaumstreet 7, 80336 Munich, Germany (e-mail: [email protected]).
Markus Jäger, M.D. [email protected]
Dr. Schennach, Mr. Obermeier, Mr. Meyer, Prof. Jäger, Dr. Seemüller, Prof. Möller, and Prof. Riedel are affiliated with the Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University, Nussbaumstreet 7, 80336 Munich, Germany (e-mail: [email protected]).
Max Schmauss, M.D.
Prof. Schmauss is with the Psychiatric Clinic, District Hospital Augsburg, Augsburg, Germany.
Gerd Laux, M.D.
Prof. Laux is with the Psychiatric Clinic, Inn-Salzach Hospital, Wasserburg-Inn, Germany.
Herbert Pfeiffer, M.D.
Dr. Pfeiffer is with the Psychiatric Clinic, Isar-Amper Hospital, Munich-Haar, Germany.
Dieter Naber, M.D.
Prof. Naber is with the Department of Psychiatry and Psychotherapy, University of Hamburg, Hamburg, Germany.
Lutz G. Schmidt, M.D.
Prof. Schmidt is with the Department of Psychiatry and Psychotherapy, University of Mainz, Mainz, Germany.
Wolfgang Gaebel, M.D.
Prof. Gaebel is with the Department of Psychiatry and Psychotherapy, Heinrich-Heine-University, Duesseldorf, Germany.
Joachim Klosterkötter, M.D.
Prof. Klosterkötter is with the Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany.
Isabella Heuser, M.D.
Prof. Heuser is with the Department of Psychiatry and Psychotherapy, Charite Berlin, Campus Benjamin Franklin, Berlin, Germany.
Wolfgang Maier, M.D.
Prof. Maier is with the Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.
Matthias R. Lemke, M.D.
Prof. Lemke is with the Department of Psychiatry, Alsterdorf Hospital, Hamburg, Germany.
Eckart Rüther, M.D.
Prof. Rüther is with the Department of Psychiatry and Psychotherapy, University of Göttingen, Göttingen, Germany.
Stefan Klingberg, M.D.
Prof. Klingberg is with the Department of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany.
Markus Gastpar, M.D.
Prof. Gastpar is with the Fliedner Clinic, Berlin, Germany.
Florian Seemüller, M.D. [email protected]
Dr. Schennach, Mr. Obermeier, Mr. Meyer, Prof. Jäger, Dr. Seemüller, Prof. Möller, and Prof. Riedel are affiliated with the Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University, Nussbaumstreet 7, 80336 Munich, Germany (e-mail: [email protected]).
Hans-Jürgen Möller, M.D. [email protected]
Dr. Schennach, Mr. Obermeier, Mr. Meyer, Prof. Jäger, Dr. Seemüller, Prof. Möller, and Prof. Riedel are affiliated with the Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University, Nussbaumstreet 7, 80336 Munich, Germany (e-mail: [email protected]).
Michael Riedel, M.D. [email protected]
Prof. Riedel is also with the Psychiatric Clinic, Vinzenz-von-Paul-Hospital, Rottweil, Germany.
Dr. Schennach, Mr. Obermeier, Mr. Meyer, Prof. Jäger, Dr. Seemüller, Prof. Möller, and Prof. Riedel are affiliated with the Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University, Nussbaumstreet 7, 80336 Munich, Germany (e-mail: [email protected]).

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