DOI: 10.1176/appi.books.9780890423370.145633
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Based on Practice Guideline for the Treatment of Patients With Substance Use Disorders, Second Edition, originally published in August 2006. A guideline watch, summarizing significant developments in the scientific literature since publication of this guideline, may be available.

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Table Reference Number
Table 1. Items to Include in an Assessment
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Table 2. Treatment Settings
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Table 3. Individual Patient Characteristics That May Influence Treatment
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Table 4. Medical Disorders Associated With Specific Substances
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Table 5. Treatments for Other Co-occurring Psychiatric Disorders in Patients With Substance Use Disorders
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Table 6. Pharmacological Treatments for Nicotine Dependence
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TABLE 7. Implementation of Pharmacotherapies for Alcohol-Dependent Patients
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Level of Intoxication



Mild to moderate

Drowsiness, pupillary constriction, slurred speech

Specific treatment is usually not required

Severe overdose (may be fatal)

Respiratory depression, stupor, coma

Requires treatment in inpatient or ER setting

May require ventilatory assistance

Use naloxone to reverse

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Implementation of Methadone, Buprenorphine, or Naltrexone


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