Sections
Neurobiology of Eating Disorders: Introduction | Clinical Phenomenology and Disease Course | Family Epidemiology and Genetics | Neurobiology of Eating Disorders | Studies of Neurotransmitters | Conclusion | References
Excerpt
Anorexia nervosa (AN) and bulimia nervosa (BN)
are disorders characterized by aberrant patterns of feeding behavior
and weight regulation and disturbances in attitudes and perceptions
toward body weight and shape. The distinguishing features of AN
are an inexplicable fear of weight gain, unrelenting obsession with
fatness, and extreme cachexia, to which the person appears strikingly
indifferent. In BN, the differentiating characteristics are binge
eating of variable frequency and intensity, usually emerging after
a period of dieting and which may or may not have been associated
with weight loss, and either self-induced vomiting or some other
means of compensation for the excess of food that is consumed. Unlike
in AN, weight does not decrease to dangerously low levels. In most
people affected with BN, feeding patterns are disrupted and satiety
may be impaired. However, although abnormally low body weight is
an exclusion for the diagnosis of BN, a significant proportion of
persons affected with this illness have a prior history of AN (Eddy et al. 2007).