Sections
Effects of Aging on Pharmacokinetics and Pharmacodynamics
Excerpt
The effect of aging on pharmacokinetics (absorption, volume
of distribution, clearance rate, and elimination half-life) and
pharmacodynamics (the effect of a drug at a given dose) is crucial
to understanding how drugs should be prescribed in the elderly patient
(J. B. Schwartz 1999; Semla and Rochon 2006).