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Alzheimer's dementia is the most common form of dementia. Depending on the population series, 50%–70% of people with dementia are diagnosed clinically as having dementia due to Alzheimer's disease (Ranginwala et al. 2008), sometimes referred to as possible or probable Alzheimer's disease by the National Institute of Neurological Disorders and Stroke criteria (McKhann et al. 1984). Although experts can make the clinical diagnosis with high reliability, in population series, the pathological changes seen in the brains of people with Alzheimer's dementia are varied. The vast majority of patients meet pathological criteria for Alzheimer's disease; a significant number of patients have other pathological findings as well, such as infarcts, Lewy bodies, and lacunes.

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