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(N = 163)
Bupropion was as efficacious as imipramine and paroxetine.
(N = 610)
Duloxetine also showed efficacy on pain measures.
(N = 370)
Mirtazapine was as efficacious as low-dose (total daily dose = 30–90
mg) amitriptyline and marginally superior to paroxetine.
(N = 921)
Venlafaxine was as efficacious as citalopram, clomipramine,
dothiepin, fluoxetine, nortriptyline, and sertraline and was more
efficacious than trazodone. It was less well tolerated than fluoxetine
and sertraline, tolerated as well as citalopram and dothiepin, and
better tolerated than clomipramine, nortriptyline, and trazodone.
NA = not applicable.
aBranconnier et al. 1983; Doraiswamy et al. 2001; Weihs et al. 2000.
bNelson et al. 2005; Raskin et al. 2007.
cHoyberg et al. 1996; Schatzberg et al. 2002.
dAllard et al. 2004; Gasto et al. 2003; Mahapatra and Hackett 1997; Oslin et al. 2003; Schatzberg and Roose 2006; Smeraldi et al. 1998; Trick et al. 2004.