In addition to anxiety, benzodiazepines are indicated for muscle tension, insomnia, status epilepticus (diazepam), myoclonic epilepsy (clonazepam), preoperative anesthesia, and alcohol withdrawal. One benzodiazepine, the triazolobenzodiazepine alprazolam, is also indicated for anxiety associated with depression (as is lorazepam), and some studies have shown that alprazolam also parallels imipramine and phenelzine in having both antipanic and antidepressant properties (see Chapter 3: "Antidepressants"). Clonazepam is also approved in the treatment of panic disorder, and it is likely that all benzodiazepines are effective in the treatment of panic if given at high enough doses.