Benzodiazepines | Nonbenzodiazepine Benzodiazepine Receptor Agonists | Ramelteon
Benzodiazepines act on the specific sites of GABA type A receptors
(GABAA) and produce hypnotic, myorelaxant,
anxiolytic, and anticonvulsant effects. Benzodiazepines approved
by the FDA for the treatment of insomnia in adults include temazepam,
estazolam, quazepam, flurazepam, and triazolam. These medications
vary mainly by elimination half-life, presence of active metabolite,
and affinity for the benzodiazepine receptor subtype (Table 51–1).