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Chapter 13. Combining Interpersonal Psychotherapy With Medication

Oriana Vesga-López, M.D.; Carlos Blanco, M.D., Ph.D.
DOI: 10.1176/appi.books.9781585623648.370949

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Excerpt

Both interpersonal psychotherapy (IPT) and antidepressants have come to be regarded as empirically supported treatments for major depressive disorder (MDD). Each treatment has its potential advantages and disadvantages. When discussing treatment selection with their patients, clinicians want to know which treatment modality is preferable for a particular patient, including when combined treatment should be recommended. Questions that often arise when discussing these topics include

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Table Reference Number
Table 13–1. Studies of interpersonal psychotherapy in major depressive disorder
Table Reference Number
Table 13–2. Studies of interpersonal psychotherapy beyond major depressive disorder

References

Brown C, Schulberg HC, Madonia MJ, et al: Treatment outcomes for primary care patients with major depression and lifetime anxiety disorders. Am J Psychiatry 153:1293–1300, 1996
[PubMed]
 
Browne G, Steiner M, Roberts J, et al: Sertraline and/or interpersonal psychotherapy for patients with dysthymic disorder in primary care: 6-month comparison with longitudinal 2-year follow-up of effectiveness and costs. J Affect Disord 68:317–330, 2002
[PubMed]
 
de Mello MF, Myczcowisk LM, Menezes PR: A randomized controlled trial comparing moclobemide and moclobemide plus interpersonal psychotherapy in the treatment of dysthymic disorder. J Psychother Pract Res 10:117–123, 2001
 
DiMascio A, Weissman MM, Prusoff BA, et al: Differential symptom reduction by drugs and psychotherapy in acute depression. Arch Gen Psychiatry 36:1450–1456, 1979
[PubMed]
 
Elkin I, Shea MT, Watkins JT, et al: National Institute of Mental Health Treatment of Depression Collaborative Research Program: general effectiveness of treatments. Arch Gen Psychiatry 46:971–982, 1989
[PubMed]
 
Endicott J, Spitzer RL: A diagnostic interview: the Schedule for Affective Disorders and schizophrenia. Arch Gen Psychiatry 35:837–844, 1978
[PubMed]
 
Frank E, Kupfer DJ, Perel JM, et al: Three-year outcomes for maintenance therapies in recurrent depression. Arch Gen Psychiatry 47:1093–1099, 1990
[PubMed]
 
Frank E, Kupfer DJ, Wagner EF, et al: Efficacy of interpersonal psychotherapy as a maintenance treatment for recurrent depression: contributing factors. Arch Gen Psychiatry 48:1053–1059, 1991
[PubMed]
 
Frank E, Swartz HA, Mallinger AG, et al: Adjunctive psychotherapy for bipolar disorder: effects of changing treatment modality. J Abnorm Psychol 108:579–587, 1999
[PubMed]
 
Frank E, Grochocinski VJ, Spanier CA, et al: Interpersonal psychotherapy and antidepressant medication: evaluation of a sequential treatment strategy in women with recurrent major depression. J Clin Psychiatry 61:51–57, 2000a
 
Frank E, Shear MK, Rucci P, et al: Influence of panic-agoraphobic spectrum symptoms on treatment response in patients with recurrent major depression. Am J Psychiatry 157:1101–1107, 2000b
 
Frank E, Kupfer DJ, Thase ME, et al: Two-year outcomes for interpersonal and social rhythm therapy in individuals with bipolar I disorder. Arch Gen Psychiatry 62:996–1004, 2005
[PubMed]
 
Institute of Medicine: Improving the Quality of Health Care for Mental and Substance-Use Conditions. Washington, DC, National Academies Press, 2006
 
Keller MB, McCullough JP, Klein DN, et al: A comparison of nefazodone, the cognitive behavioral-analysis system of psychotherapy, and their combination for the treatment of chronic depression. N Engl J Med 342:1462–1470, 2000
[PubMed]
 
Klein DF, Ross DC: Reanalysis of the National Institute of Mental Health Treatment of Depression Collaborative Research Program General Effectiveness Report. Neuropsychopharmacology 8:241–251, 1993
[PubMed]
 
Klerman GL, Dimascio A, Weissman M, et al: Treatment of depression by drugs and psychotherapy. Am J Psychiatry 131:186–191, 1974
[PubMed]
 
Krupnick JL, Sotsky SM, Simmens S, et al: The role of the therapeutic alliance in psychotherapy and pharmacotherapy outcome: findings in the National Institute of Mental Health Treatment of Depression Collaborative Research Program. J Consult Clin Psychol 64:532–539, 1996
[PubMed]
 
Lespérance F, Frasure-Smith N, Koszycki D, et al; CREATE Investigators: Effects of citalopram and interpersonal psychotherapy on depression in patients with coronary artery disease: the Canadian Cardiac Randomized Evaluation of Antidepressant and Psychotherapy Efficacy (CREATE) trial. JAMA 297:367–379, 2007
[PubMed]
 
Markowitz JC, Kocsis JH, Fishman B, et al: Treatment of HIV-positive patients with depressive symptoms. Arch Gen Psychiatry 55:452–457, 1998
[PubMed]
 
Markowitz JC, Kocsis JH, Bleiberg KL, et al: A comparative trial of psychotherapy and pharmacotherapy for "pure" dysthymic patients. J Affect Disord 89:167–175, 2005
[PubMed]
 
Mufson L, Moreau D, Weissman MM, et al: Modification of interpersonal psychotherapy with depressed adolescents (IPT-A): phase I and II studies. J Am Acad Child Adolesc Psychiatry 33:695–705, 1994
[PubMed]
 
Mufson L, Weissman MM, Moreau D, et al: Efficacy of interpersonal psychotherapy for depressed adolescents. Arch Gen Psychiatry 56:573–579, 1999
[PubMed]
 
Mufson L, Dorta KP, Wickramaratne P, et al: A randomized effectiveness trial of interpersonal psychotherapy for depressed adolescents. Arch Gen Psychiatry 61:577–584, 2004
[PubMed]
 
Paykel ES, Dimascio A, Haskell D, et al: Effects of maintenance amitriptyline and psychotherapy on symptoms of depression. Psychol Med 5:67–77, 1975
[PubMed]
 
Posternak MA, Zimmerman M: Is there a delay in the antidepressant effect? A meta-analysis. J Clin Psychiatry 66:148–158, 2005
[PubMed]
 
Quitkin FM, McGrath PJ, Stewart JW, et al: Chronological milestones to guide drug change. When should clinicians switch antidepressants? Arch Gen Psychiatry 53:785–792, 1996
[PubMed]
 
Quitkin FM, Petkova E, McGrath PJ, et al: When should a trial of fluoxetine for major depression be declared failed? Am J Psychiatry 160:734–740, 2003
[PubMed]
 
Quitkin FM, McGrath PJ, Stewart JW, et al: Remission rates with 3 consecutive antidepressant trials: effectiveness for depressed outpatients. J Clin Psychiatry 66:670–676, 2005
[PubMed]
 
Reynolds CF 3rd, Frank E, Perel JM, et al: Nortriptyline and interpersonal psychotherapy as maintenance therapies for recurrent major depression: a randomized controlled trial in patients older than 59 years. JAMA 281:39–45, 1999
[PubMed]
 
Reynolds CF 3rd, Dew MA, Pollock BG, et al: Maintenance treatment of major depression in old age. N Engl J Med 354:1130–1138, 2006
[PubMed]
 
Roy-Byrne P, Russo J, Dugdale DC, et al: Undertreatment of panic disorder in primary care: role of patient and physician characteristics. J Am Board Fam Pract 15:443–450, 2002
[PubMed]
 
Schulberg HC, Block MR, Madonia MJ, et al: Treating major depression in primary care practice: eight-month clinical outcomes. Arch Gen Psychiatry 53:913–919, 1996
[PubMed]
 
Shea MT, Elkin I, Imber SD, et al: Course of depressive symptoms over follow-up: findings from the National Institute of Mental Health Treatment of Depression Collaborative Research Program. Arch Gen Psychiatry 49:782–787, 1992
[PubMed]
 
Sotsky SM, Glass DR, Shea MT, et al: Patient predictors of response to psychotherapy and pharmacotherapy: findings in the NIMH Treatment of Depression Collaborative Research Program. Am J Psychiatry 148:997–1008, 1991
[PubMed]
 
Spinelli MG: Interpersonal psychotherapy for depressed antepartum women: a pilot study. Am J Psychiatry 154:1028–1030, 1997
[PubMed]
 
Spinelli MG, Endicott J: Controlled clinical trial of interpersonal psychotherapy versus parenting education program for depressed pregnant women. Am J Psychiatry 160:555–562, 2003
[PubMed]
 
Taylor MJ, Freemantle N, Geddes JR, et al: Early onset of selective serotonin reuptake inhibitor antidepressant action: systematic review and meta-analysis. Arch Gen Psychiatry 63:1217–1223, 2006
[PubMed]
 
Thase ME, Buysse DJ, Frank E, et al: Which depressed patients will respond to interpersonal psychotherapy? The role of abnormal EEG sleep profiles. Am J Psychiatry 154:502–509, 1997a
 
Thase ME, Greenhouse JB, Frank E, et al: Treatment of major depression with psychotherapy or psychotherapy-pharmacotherapy combinations. Arch Gen Psychiatry 54:1009–1015, 1997b
 
Weissman MM, Klerman GL, Paykel ES, et al: Treatment effects on the social adjustment of depressed patients. Arch Gen Psychiatry 30:771–778, 1974
[PubMed]
 
Weissman MM, Prusoff BA, Dimascio A, et al: The efficacy of drugs and psychotherapy in the treatment of acute depressive episodes. Am J Psychiatry 136:555–558, 1979
[PubMed]
 
Weissman MM, Klerman GL, Prusoff BA, et al: Depressed outpatients: results one year after treatment with drugs and/or interpersonal psychotherapy. Arch Gen Psychiatry 38:51–55, 1981
[PubMed]
 
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