Table 2. Cholinesterase Inhibitors and Memantine
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cholinesterase inhibitorsin alzheimer's diseasememantinein alzheimer's diseaseTable 2. Cholinesterase Inhibitors and Memantine
|Medication||Usual Starting Dose (mg/day)||Usual Target Dose (mg/day)||Side Effects|
Cholinergic effects, including nausea,
vomiting, decreased appetite and weight, bradycardia, muscle cramps,
and increased gastrointestinal acid. May induce or exacerbate urinary
obstruction, worsen asthma or chronic obstructive pulmonary disease,
cause seizures, induce or worsen sleep disturbance, and exaggerate
the effects of some muscle relaxants during anesthesia.
Infrequent effects: mild confusion, dizziness, headache, sedation,
agitation, falls, and constipation.