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In general, use low starting doses, small dose increases, and long intervals between dose increases.

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  • Elderly individuals have decreased renal clearance and slowed hepatic metabolism, which alters the pharmacokinetics of many medications. Moreover, because elderly individuals may have multiple coexisting medical conditions and therefore may take multiple medications, it is important to consider how these general medical conditions and associated medications may interact to further alter the absorption, serum protein binding, metabolism, and excretion of the medication.

  • Some patients may ultimately need doses as high as would be appropriate for younger patients.

  • See Tables 2, 3, 4, and 5 for usual doses and side effects for commonly prescribed first-line medications.

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Table 2. Cholinesterase Inhibitors and Memantine

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Table Reference Number
Table 2. Cholinesterase Inhibitors and Memantine
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Table 3. Second-Generation Antipsychotics

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Table 3. Second-Generation Antipsychotics
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Table 4. Antidepressants

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Table 4. Antidepressants
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Table 5. Medications to Treat Sleep Disturbance

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Table 5. Medications to Treat Sleep Disturbance
Table Reference Number
Table 2. Cholinesterase Inhibitors and Memantine
Table Reference Number
Table 3. Second-Generation Antipsychotics
Table Reference Number
Table 4. Antidepressants
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Table 5. Medications to Treat Sleep Disturbance

References

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