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Psychotherapy and Other Psychosocial Treatments

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Recent studies have provided additional support for the efficacy of a number of psychosocial treatment approaches, including problem-solving treatment (65, 66), group psychoeducation (65), and the cognitive behavioral analysis system of psychotherapy (67). Additional meta-analyses have suggested that among psychotherapeutic approaches, other bona fide psychotherapies have efficacy comparable with CBT for treating depression (68, 69), although more research with CBT has been done. Given the evidence for the benefits of exercise in older depressed adults (70, 71), exercise may also be of value in other subgroups of patients with major depression.

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Psychotherapy combined with pharmacotherapy

As noted in the guideline, studies examining combination treatment with psychotherapy and pharmacotherapy have shown mixed results. Although this has continued to be true in subsequently published studies (66, 67, 72, 73), a recent meta-analysis suggested that a combination of psychotherapy and pharmacotherapy is more effective than pharmacotherapy alone (74). Combination therapy may be particularly useful in improving treatment adherence (73, 74) and might be of some use in targeting particular symptoms or patient subgroups (75–77).

References

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