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Insights From Adoption and Twin Studies | Psychiatric Disorders Are Complex Genetic Disorders | Response to Drug Treatment
Excerpt
Genetic epidemiological studies have established that most
psychiatric disorders, as well as many nonpathological human behavioral
traits, have a substantial genetic component. Investigations in
genetic epidemiology therefore provide the scientific foundation
for molecular genetic and genomic studies of human behavior and
behavioral disorders (Kendler 1993, 2001; Plomin and Kosslyn 2001). Genetic epidemiology uses family, twin,
and adoption studies to assess the contribution of familial, environmental,
and genetic factors to a trait of interest. Family studies can establish
that a given disorder "runs in families" but cannot
easily distinguish whether such familiality is due to genetic or
environmental factors. An everyday example of the distinction between genetic and familial (but
environmental) traits is the difference between the ability to acquire
language (a genetic trait that distinguishes
humans from other species) and the native language spoken by a given
person, which is familial, but entirely
environmentally determined.