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Body to Brain: Immune System Effects on Central Nervous System Functioning

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The field of psychoneuroimmunology is based on the existence of bidirectional communication pathways between the brain and the immune system. This implies that just as the CNS is capable of modulating immunity, the immune system can alter functioning within the CNS. Although researchers historically were first interested in pathways by which the brain affects immunity, the past 10–15 years have seen a groundswell of interest in the ways in which the immune system contributes to the development of psychopathology.

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Table Reference Number
TABLE 9–3. Evidence that cytokines can alter central nervous system function
Table Reference Number
TABLE 9–4. Potential mechanisms by which cytokines may influence behavior

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