Pharmacological Profile

The American Psychiatric Publishing Textbook of Psychopharmacology, 4th Edition >

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Pharmacological Profile

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Serotonin | Norepinephrine | Dopamine

Excerpt

The action of any SSRI extends beyond the inhibition of 5-HT reuptake. At least 14 different 5-HT receptor subtypes reside at pre- and postsynaptic locations (Fuller 1996). Serotonin_1A (5-HT_1A) binding sites include both somatodendritic and presynaptic autoreceptors (which inhibit 5-HT firing) and postsynaptic receptors. The latter are predominantly hippocampal, and their sensitivity is increased after chronic antidepressant exposure (Aghajanian et al. 1988; Elena Castro et al. 2003).

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NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s “Cited By” API will populate this tab (http://www.crossref.org/citedby.html).

Compression-Only CPR: Pushing the Science Forward
Cone
AAM 2010;304:1493-1495.

All you need to read in the other general journals
BMJ 2010;341:c5893-c1494.

Pharmacological Profile

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