Major and Atypical Depression | Panic Disorder | Social Phobia | Obsessive-Compulsive Disorder | Posttraumatic Stress Disorder | Generalized Anxiety Disorder | Bulimia Nervosa | Premenstrual Dysphoria | Chronic Pain | Neurological Diseases
Many studies have examined the efficacy of
MAOIs in the treatment of different types of depression. MAOIs have been
effective in the treatment of major depression or atypical depression
(Davidson et al. 1987a; Himmelhoch et al. 1982, 1991; Johnstone 1975; Johnstone and Marsh 1973; McGrath et al. 1986; Paykel et al. 1982; Quitkin et al. 1979, 1990, 1991; Rowan et al. 1981; Thase et al. 1992; Vallejo et al. 1987; White et al. 1984); Zisook et al. 1985). Although early studies of relatively low-dose
regimens suggested that the efficacy of MAOIs was lower than that of
TCAs, more recent studies have documented that their efficacy is
comparable (Table 18–2).