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The summary statement by the American Psychiatric Association Task Force on Electroconvulsive Therapy (2001) and research over the past 30 years (Abrams 1992; Fink 1979; O'Connor et al. 2001; Petrides et al. 2001) have confirmed that ECT is an effective treatment for depression in more than 80% of patients with treatment-resistant unipolar major depression or bipolar disorder. A meta-analysis of randomized, controlled trials (RCTs) performed by the UK ECT Review Group (2003) confirmed the following about the efficacy of ECT for major depression:

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