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Cognitive-perceptual symptoms, such as paranoia, perceptual aberrations, and subtle thought disorder, although not figuring as prominently in the diagnosis of Cluster B as in Cluster A personality disorders, are definitely present in at least a subgroup of BPD patients, especially under periods of stress and decompensation. The presence of such target symptoms, more prominent in the older BPD trials that included schizotypal subgroups of patients, was the impetus for the early neuroleptic trials. Studies from the late 1970s and early 1980s began to report some efficacy of low-dose neuroleptics in treating BPD, although these studies were not placebo controlled (Brinkley et al. 1979; Leone 1982).

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Table Reference Number
TABLE 61–1. Summary of medication treatment trials with antipsychotics in borderline personality disorder (BPD)
Table Reference Number
TABLE 61–2. Summary of medication treatment trials with antidepressants in borderline personality disorder (BPD)
Table Reference Number
TABLE 61–3. Summary of medication treatment trials with mood stabilizers in borderline personality disorder (BPD)

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