Conventional Antipsychotics | Atypical Antipsychotics | Antidepressants | Mood Stabilizers | Other Medications
Cognitive-perceptual symptoms, such as paranoia, perceptual
aberrations, and subtle thought disorder, although not figuring
as prominently in the diagnosis of Cluster B as in Cluster A personality
disorders, are definitely present in at least a subgroup of BPD
patients, especially under periods of stress and decompensation.
The presence of such target symptoms, more prominent in the older BPD
trials that included schizotypal subgroups of patients, was the
impetus for the early neuroleptic trials. Studies from the late
1970s and early 1980s began to report some efficacy of low-dose
neuroleptics in treating BPD, although these studies were not placebo
controlled (Brinkley et al. 1979; Leone 1982).