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Phencyclidine (PCP), commonly referred to as "angel dust," inhibits catecholamine reuptake in neurons, leading to adrenergic potentiation (Greydanus and Patel 2003). It was initially developed in the 1950s to be used as an anesthetic, but it was never approved for human use due to its significant adverse effects, including intensely negative psychological ones. It can be used as a liquid, tablet, or powder and can also be sprinkled on a cigarette. Results from the Monitoring the Future survey reveal that in 2005, 2.4% of high school seniors reported a lifetime use of PCP; annual use was reported by 1.3% of seniors, and 30-day use was reported by 0.7% (National Institute on Drug Abuse 2005a).

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