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The family of anabolic–androgenic steroids (AASs) includes testosterone and its synthetic derivatives. AASs have long been recognized as substances of abuse in athletes and bodybuilders because the drugs can enhance endurance and performance. They are also abused among male adolescents and young adults to gain muscle mass and lose fat. In 2005, results from the Monitoring the Future study revealed that 2.6% of high school seniors had reported using steroids at least once (National Institute on Drug Abuse 2005b).

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