Complaints of pain are the most common reason for patient presentations to ambulatory medical settings (Schappert 1992), accounting for approximately 35 million office visits annually (Knapp and Koch 1984). Most of these remit spontaneously or respond to simple treatment interventions; however, as many as one-fourth of these symptoms remain chronic (Schappert 1992). Chronic pain is pervasive; clinicians in a variety of specialties are likely to encounter patients with pain who present treatment challenges. The costs of chronic pain are monumental when health care, absenteeism, lost wages, and disability are considered (Fishman et al. 1997; Loeser 1999; Stewart et al. 2003). The pervasiveness, refractoriness, and costs associated with chronic pain have rendered chronic pain management a public health priority, spurring multiple efforts directed at understanding the pathophysiological processes underlying pain and at refining treatment strategies. Because of the complexities involved in the experience of pain, its management requires a comprehensive assessment and the implementation of multimodal treatment strategies, including psychopharmacological and psychosocial interventions.