Background | Clinical Use | Risks, Side Effects, and Their Management | Overdose
Trazodone is an antidepressant that is associated with significant
sedation. Currently, trazodone is not recommended as a first-line
antidepressant because of an increased risk of orthostatic hypotension,
arrhythmias, and priapism. However, trazodone may be useful in some
patients with insomnia (although the use of trazodone specifically
for insomnia is not approved by the FDA).