Pharmacotherapy for Acute Major Depression | Pharmacotherapy for Depression With Psychotic Features | Pharmacotherapy for Bipolar Depression | Maintenance Treatment of Major Depression | Treatment-Resistant Depression | Pharmacotherapy for Borderline Personality Disorder
In patients receiving antidepressants for acute major depression,
the initial therapeutic response is often delayed by several weeks.
Clinicians should discuss the potential delay of symptomatic improvement
with their patients when prescribing antidepressants so that patients
will enter treatment with informed and realistic treatment expectations;
otherwise, patients may become frustrated or discouraged if they do
not see immediate improvement in symptoms and may prematurely discontinue
the medication or not return for further care.