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Chapter 5. Structural Imaging

Erin D. Bigler, Ph.D.
DOI: 10.1176/appi.books.9781585624201.673559

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Structural imaging refers to various techniques that generate static views of the brain, primarily using the methods of computed tomography (CT) and magnetic resonance (MR) imaging (MRI). The brain can be readily compartmentalized into three areas: white matter (WM), gray matter (GM), and cerebral spinal fluid (CSF)–filled spaces or cavities. Brain tissue has its own vasculature and blood vessels that can be separately imaged using structural imaging techniques, but the totality of the brain's vasculature makes up a small percentage of total brain volume. Because of the water content of blood and the makeup of cerebral vessels, most of the cerebral vasculature gets classified within the spectrum of CSF or of the parenchymal tissue where a vessel is embedded using standard imaging sequences. Thus, the microvasculature within GM and WM (unless a disease state exists or a hemorrhage has occurred) becomes classified as the tissue that it is embedded in. From a structural imaging and gross anatomy perspective, this general rule of WM, GM, or CSF classification applies for any region of interest.

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