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Physostigmine (not recommended)
Cholinesterase inhibitors (donepezil, rivastigmine,
Psychostimulants (methylphenidate, dextroamphetamine)
? Other antidepressants (SSRIs, SNRIs, bupropion)
? Atomoxetine (selective norepinephrine reuptake inhibitor)
? Pergolide, pramipexole, ropinirole (dopamine receptor
? Guanfacine (selective 2A-adrenergic
? Memantine (N-methyl-d-aspartate
Note. SNRIs = serotonin-norepinephrine
reuptake inhibitors; SSRIs = selective serotonin reuptake
inhibitors. "?" indicates potentially useful agents
that have very limited or no support within the clinical traumatic
brain injury literature. See text for details.