Agonist Maintenance Treatment

Richard S. Schottenfeld, M.D.



Opioid dependence is a chronic and severe disorder associated with substantial risk of mortality, morbidity, and adverse social, vocational, familial, and legal consequences. The goals of treatment are to prevent or reduce the adverse consequences and to improve the patient's functioning and quality of life. Opioid agonist maintenance treatment generally refers to a comprehensive approach, including medications in combination with drug counseling, behavioral monitoring, and provision of or referral to psychiatric, medical, or vocational services. Since its development in the 1960s, this approach has proven to be the most effective treatment for opioid dependence.

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Table Reference Number
Table 14C–1. Medication interactions


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