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Chapter 24. Neurocognitive Disorders

Myron Weiner, M.D.
DOI: 10.1176/appi.books.9781585625031.171910

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Excerpt

The neurocognitive disorders encompass DSM-IV-TR (American Psychiatric Association 2000) cognitive disorders—delirium, dementia, and other cognitive disorders designated in early DSM editions as organic mental disorders. “Organic” mental disorders were conceptualized as the product of structural or physiological changes in brain tissue. By contrast, functional disorders were presumed to result from aberrations in processes that were entirely mental. It has become increasingly evident that the line between organic and functional disorders is unclear and that many “functional” disorders such as schizophrenia are in fact related to abnormalities of brain development and structure.

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In vivo amyloid imaging.Florbetapir imaging (coronal view) shows no amyloid accumulation in the brain of a normal control subject (NC) and extensive accumulation in the brain of a patient with Alzheimer’s disease (AD).Source. Image courtesy of Dr. M. D. Devous, Sr.
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DSM-5 neurocognitive disorders
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Laboratory aids to diagnosis of neurocognitive disorders
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Verbal learning and memory features in neurocognitive disorders
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Differential diagnosis of delirium, neurocognitive disorder, and depression
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Inpatient management of delirium
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Possible etiologies of mild cognitive impairment (MCI)
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Diagnostic features of the most common neurocognitive disorders in adults
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Dosages of commonly used cholinesterase inhibitors

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