No access

Article

Published Online: November 1939

A COMPARATIVE STUDY OF HYPOGLYCEMIC SHOCK TREATMENT AND CONTROL OBSERVATION IN SCHIZOPHRENIA

J. NOTKIN, C. E. NILES, F. J. DENATALE, and G. WITTMANAuthors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 96, Number 3

https://doi.org/10.1176/ajp.96.3.681

Get Access

Abstract

A group of 100 patients of the predominantly chronic type of schizophrenia, equally divided by sex, underwent a course of hypoglycemic shock treatment while 69 patients—36 men and 33 women—were observed as controls. Fifteen other patients, eight men and seven women have improved spontaneously while in preparation for treatment. The report is based on the state of the patients eight months to two years after termination of treatment or control observation.

Various degrees of improvement took place in 36 per cent of the treated patients, a lower percentage than generally reported.

The percentage of improvement in the control group was 21.7.

The percentage of improvement in the combined control and spontaneously improved group was 35.7 or about the same as in the treated group.

Relapses took place in 47 per cent of the treated patients, in 33.3 per cent of control cases and in 24 per cent of the combined control and spontaneously improved patients.

The treatment was the cause of death in 3 per cent of cases.

"Recovery" occurred in only slightly over 7 per cent among treated patients with psychosis of not more than 18 months' duration.

The same rate of "recovery" took place among the combined control and spontaneously improved patients with psychosis of less than si months' duration.

The percentage of "improved" ranged from 75.0 to 21.5 in the treated group, from 75.0 to 8.8 in the control group and from 57.0 to 12.2 in the combined control and spontaneously improved group, in proportion to the duration of the psychosis.

"Lack of improvement" ranged from 12.5 per cent to 78.5 per cent in the treated group, from 25.0 per cent to 86.8 per cent in the control group and from 7.2 per cent to 79.7 per cent in the combined control and spontaneously improved group, in proportion to the duration of the psychosis.

The duration of the psychosis in the improved treated, improved control and in the spontaneously improved patients was shorter than in the unimproved patients.

The highest percentage of relapses occurred among patients with psychosis of longer duration.

Both treated and control patients with psychosis of shorter duration had the longest lasting remissions.

Get full access to this article

View all available purchase options and get full access to this article.

Get Access

Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 96 • Number 3 • November 1939

Pages: 681 - 688

History

Published in print: November 1939

Published online: 1 April 2006

Authors

Details

J. NOTKIN

Hudson River State Hospital, Poughkeepsie, N. Y.

View all articles by this author

C. E. NILES

Hudson River State Hospital, Poughkeepsie, N. Y.

View all articles by this author

F. J. DENATALE

Hudson River State Hospital, Poughkeepsie, N. Y.

View all articles by this author

G. WITTMAN

Hudson River State Hospital, Poughkeepsie, N. Y.

View all articles by this author

Metrics & Citations

Metrics

Citations

Export Citations

If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click Download.

For more information or tips please see 'Downloading to a citation manager' in the Help menu.

Format	RIS (ProCite, Reference Manager) EndNote BibTex Medlars RefWorks
Direct importt
Citation style
Style

Copy to clipboard
Tips for downloading citations

View Options

Get Access

Login options

Already a subscriber? Access your subscription through your login credentials or your institution for full access to this article.

Personal login Institutional Login Open Athens login

Purchase Options

Purchase this article to access the full text.

PPV Articles - American Journal of Psychiatry

Not a subscriber?

Subscribe Now / Learn More

PsychiatryOnline subscription options offer access to the DSM-5-TR^® library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development.

Need more help? PsychiatryOnline Customer Service may be reached by emailing [email protected] or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.).

A COMPARATIVE STUDY OF HYPOGLYCEMIC SHOCK TREATMENT AND CONTROL OBSERVATION IN SCHIZOPHRENIA

Abstract

Get full access to this article