EFFECTS OF CHEMICAL STIMULATION TO DISCRETE BRAIN AREAS

ROBERT G. HEATH and FLORIS de BALBIAN VERSTERAuthors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 117, Number 11

https://doi.org/10.1176/ajp.117.11.980

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Abstract

A cannula, and a method for its accurate implantation into predetermined brain regions, is described. This technique makes possible the accurate injection of minute quantities of chemicals into specific deep regions of the brain. The behavioral effects and concomitant changes in electrical recordings from subcortical structures induced by the injection of a variety of compounds and brain extracts into selected brain regions of cats, monkeys, and humans are described. The most consistent and dramatic changes were induced with the injection of bovine septal extract, histamine, and atropine.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 117 • Number 11 • May 1961

Pages: 980 - 990

PubMed: 13712615

History

Published in print: May 1961

Published online: 1 April 2006

Authors

Details

ROBERT G. HEATH

Tulane University School of Medicine, New Orleans, La.

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FLORIS de BALBIAN VERSTER

Tulane University School of Medicine, New Orleans, La.

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EFFECTS OF CHEMICAL STIMULATION TO DISCRETE BRAIN AREAS

Abstract

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