CLINICAL EVALUATION OF PACATAL

PAUL E. FELDMANAuthors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 114, Number 2

https://doi.org/10.1176/ajp.114.2.143

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Abstract

1. Pacatal is capable of eliciting therapeutic responses in chronically psychotic patients.

2. It is most efficacious for those aspects of behavior which are related to increased anxiety and least efficacious for judgment, insight, orientation, memory and affect.

3. The clinically significant side-effects are those related to the atropine-like action of Pacatal. Untreated eye complications, following prolonged administration of Pacatal, may lead to ulceration of the corneal epithelium.

4. It is recommended that any prolonged ocular disturbance as a result of Pacatal medication be treated with Neostigmine.

5. All the side-effects produced by Pacatal can be obliterated by symptomatic medication, lowering of daily dosage or discontinuation of the medication.

6. The results obtained with Pacatal are encouraging and warrant further investigation upon a prognostically better group of psychotic patients.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 114 • Number 2 • August 1957

Pages: 143 - 146

PubMed: 13444479

History

Published in print: August 1957

Published online: 1 April 2006

Authors

Details

PAUL E. FELDMAN

Director of Research and Education, Topeka State Hospital, Topeka, Kansas.

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CLINICAL EVALUATION OF PACATAL

Abstract

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