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Windows to the Brain
Published Online: 1 October 2011

Central Pontine Myelinolysis: A Metabolic Disorder of Myelin

Robin A. Hurley, M.D., Christopher M. Filley, M.D., and Katherine H. Taber, Ph.D.Authors Info & Affiliations
Publication: The Journal of Neuropsychiatry and Clinical Neurosciences
Volume 23, Number 4
https://doi.org/10.1176/jnp.23.4.jnp369
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Abstract

This issue's Windows to the Brain series describes this heterogeneous condition, in which demyelinization occurs because of nutritional or electrolyte stress, that is, imbalance due to overly-rapid correction of hyponatremia, often in the presence of alcoholism, liver disease, immunosuppression after transplantation, malnutrition, renal disease, cancer, pregnancy, and in high-endurance exercise. The authors describe evaluation procedures and the considerable variation in clinical course and outcome.

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Published In

Go to The Journal of Neuropsychiatry and Clinical Neurosciences
Go to The Journal of Neuropsychiatry and Clinical Neurosciences
The Journal of Neuropsychiatry and Clinical Neurosciences
Volume 23 • Number 4 • Fall 2011
Pages: 369 - 374
PubMed: 22231306

History

Received: 13 September 2011
Published online: 1 October 2011
Published in print: Fall 2011

Authors

Details

Robin A. Hurley, M.D.
Drs. Hurley and Taber are affiliated with the Veterans Affairs Mid-Atlantic Mental Illness Research, Education, and Clinical Center, and the Research and Education Service Line at the W.G. Hefner Veterans Affairs Medical Center in Salisbury, NC. Dr. Hurley is affiliated with the Departments of Psychiatry and Radiology at Wake Forest University School of Medicine in Winston-Salem, NC, and the Menninger Department of Psychiatry and Behavioral Sciences at Baylor College of Medicine in Houston, TX. Dr. Filley is Director of the Behavioral Section, and Professor of Neurology and Psychiatry at the University of Colorado School of Medicine, and Neurology Service Chief at the Denver Veterans Affairs Medical Center in Denver, CO. Dr. Taber is affiliated with the Division of Biomedical Sciences at the Edward Via College of Osteopathic Medicine in Blacksburg, VA, and the Department of Physical Medicine and Rehabilitation at Baylor College of Medicine in Houston, TX.
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Christopher M. Filley, M.D.
Drs. Hurley and Taber are affiliated with the Veterans Affairs Mid-Atlantic Mental Illness Research, Education, and Clinical Center, and the Research and Education Service Line at the W.G. Hefner Veterans Affairs Medical Center in Salisbury, NC. Dr. Hurley is affiliated with the Departments of Psychiatry and Radiology at Wake Forest University School of Medicine in Winston-Salem, NC, and the Menninger Department of Psychiatry and Behavioral Sciences at Baylor College of Medicine in Houston, TX. Dr. Filley is Director of the Behavioral Section, and Professor of Neurology and Psychiatry at the University of Colorado School of Medicine, and Neurology Service Chief at the Denver Veterans Affairs Medical Center in Denver, CO. Dr. Taber is affiliated with the Division of Biomedical Sciences at the Edward Via College of Osteopathic Medicine in Blacksburg, VA, and the Department of Physical Medicine and Rehabilitation at Baylor College of Medicine in Houston, TX.
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Katherine H. Taber, Ph.D.
Drs. Hurley and Taber are affiliated with the Veterans Affairs Mid-Atlantic Mental Illness Research, Education, and Clinical Center, and the Research and Education Service Line at the W.G. Hefner Veterans Affairs Medical Center in Salisbury, NC. Dr. Hurley is affiliated with the Departments of Psychiatry and Radiology at Wake Forest University School of Medicine in Winston-Salem, NC, and the Menninger Department of Psychiatry and Behavioral Sciences at Baylor College of Medicine in Houston, TX. Dr. Filley is Director of the Behavioral Section, and Professor of Neurology and Psychiatry at the University of Colorado School of Medicine, and Neurology Service Chief at the Denver Veterans Affairs Medical Center in Denver, CO. Dr. Taber is affiliated with the Division of Biomedical Sciences at the Edward Via College of Osteopathic Medicine in Blacksburg, VA, and the Department of Physical Medicine and Rehabilitation at Baylor College of Medicine in Houston, TX.
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Notes

Address correspondence to Dr. Robin Hurley, Hefner VA Medical Center, Salisbury, NC; [email protected] (e-mail).

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