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Published Online: 1 December 2011

The Columbia–Suicide Severity Rating Scale: Initial Validity and Internal Consistency Findings From Three Multisite Studies With Adolescents and Adults

Abstract

The Columbia–Suicide Severity Rating Scale was initially designed to assess suicidal ideation and behavior in clinical trials. Psychometric analysis of data on adolescents indicated that a lifetime history of worst-point suicidal ideation including either suicidal intent or intent with a plan predicts a future risk of an actual attempt that is four times as great as the risk associated with a history of current suicidal ideation—including a desire to be dead—or increased general ratings of depression.

Abstract

Objective:

Research on suicide prevention and interventions requires a standard method for assessing both suicidal ideation and behavior to identify those at risk and to track treatment response. The Columbia–Suicide Severity Rating Scale (C-SSRS) was designed to quantify the severity of suicidal ideation and behavior. The authors examined the psychometric properties of the scale.

Method:

The C-SSRS's validity relative to other measures of suicidal ideation and behavior and the internal consistency of its intensity of ideation subscale were analyzed in three multisite studies: a treatment study of adolescent suicide attempters (N=124); a medication efficacy trial with depressed adolescents (N=312); and a study of adults presenting to an emergency department for psychiatric reasons (N=237).

Results:

The C-SSRS demonstrated good convergent and divergent validity with other multi-informant suicidal ideation and behavior scales and had high sensitivity and specificity for suicidal behavior classifications compared with another behavior scale and an independent suicide evaluation board. Both the ideation and behavior subscales were sensitive to change over time. The intensity of ideation subscale demonstrated moderate to strong internal consistency. In the adolescent suicide attempters study, worst-point lifetime suicidal ideation on the C-SSRS predicted suicide attempts during the study, whereas the Scale for Suicide Ideation did not. Participants with the two highest levels of ideation severity (intent or intent with plan) at baseline had higher odds for attempting suicide during the study.

Conclusions:

These findings suggest that the C-SSRS is suitable for assessment of suicidal ideation and behavior in clinical and research settings.

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Information & Authors

Information

Published In

Go to American Journal of Psychiatry
Go to American Journal of Psychiatry
American Journal of Psychiatry
Pages: 1266 - 1277
PubMed: 22193671

History

Received: 29 November 2010
Revision received: 18 May 2011
Revision received: 26 July 2011
Accepted: 1 August 2011
Published online: 1 December 2011
Published in print: December 2011

Authors

Details

Kelly Posner, Ph.D.
From the Department of Psychiatry and the Division of Child and Adolescent Psychiatry, Columbia University, College of Physicians and Surgeons, and New York State Psychiatric Institute, New York; Department of Psychiatry, University of Pennsylvania, Philadelphia; University of Pittsburgh School of Medicine and Western Psychiatric Institute and Clinic, Pittsburgh; Department of Psychiatry, University of Rochester Medical Center, Rochester, N.Y.; and the Monash University Centre for Developmental Psychiatry and Psychology, Victoria, Australia.
Gregory K. Brown, Ph.D.
From the Department of Psychiatry and the Division of Child and Adolescent Psychiatry, Columbia University, College of Physicians and Surgeons, and New York State Psychiatric Institute, New York; Department of Psychiatry, University of Pennsylvania, Philadelphia; University of Pittsburgh School of Medicine and Western Psychiatric Institute and Clinic, Pittsburgh; Department of Psychiatry, University of Rochester Medical Center, Rochester, N.Y.; and the Monash University Centre for Developmental Psychiatry and Psychology, Victoria, Australia.
Barbara Stanley, Ph.D.
From the Department of Psychiatry and the Division of Child and Adolescent Psychiatry, Columbia University, College of Physicians and Surgeons, and New York State Psychiatric Institute, New York; Department of Psychiatry, University of Pennsylvania, Philadelphia; University of Pittsburgh School of Medicine and Western Psychiatric Institute and Clinic, Pittsburgh; Department of Psychiatry, University of Rochester Medical Center, Rochester, N.Y.; and the Monash University Centre for Developmental Psychiatry and Psychology, Victoria, Australia.
David A. Brent, M.D.
From the Department of Psychiatry and the Division of Child and Adolescent Psychiatry, Columbia University, College of Physicians and Surgeons, and New York State Psychiatric Institute, New York; Department of Psychiatry, University of Pennsylvania, Philadelphia; University of Pittsburgh School of Medicine and Western Psychiatric Institute and Clinic, Pittsburgh; Department of Psychiatry, University of Rochester Medical Center, Rochester, N.Y.; and the Monash University Centre for Developmental Psychiatry and Psychology, Victoria, Australia.
Kseniya V. Yershova, Ph.D.
From the Department of Psychiatry and the Division of Child and Adolescent Psychiatry, Columbia University, College of Physicians and Surgeons, and New York State Psychiatric Institute, New York; Department of Psychiatry, University of Pennsylvania, Philadelphia; University of Pittsburgh School of Medicine and Western Psychiatric Institute and Clinic, Pittsburgh; Department of Psychiatry, University of Rochester Medical Center, Rochester, N.Y.; and the Monash University Centre for Developmental Psychiatry and Psychology, Victoria, Australia.
Maria A. Oquendo, M.D.
From the Department of Psychiatry and the Division of Child and Adolescent Psychiatry, Columbia University, College of Physicians and Surgeons, and New York State Psychiatric Institute, New York; Department of Psychiatry, University of Pennsylvania, Philadelphia; University of Pittsburgh School of Medicine and Western Psychiatric Institute and Clinic, Pittsburgh; Department of Psychiatry, University of Rochester Medical Center, Rochester, N.Y.; and the Monash University Centre for Developmental Psychiatry and Psychology, Victoria, Australia.
Glenn W. Currier, M.D., M.P.H.
From the Department of Psychiatry and the Division of Child and Adolescent Psychiatry, Columbia University, College of Physicians and Surgeons, and New York State Psychiatric Institute, New York; Department of Psychiatry, University of Pennsylvania, Philadelphia; University of Pittsburgh School of Medicine and Western Psychiatric Institute and Clinic, Pittsburgh; Department of Psychiatry, University of Rochester Medical Center, Rochester, N.Y.; and the Monash University Centre for Developmental Psychiatry and Psychology, Victoria, Australia.
Glenn A. Melvin, Ph.D.
From the Department of Psychiatry and the Division of Child and Adolescent Psychiatry, Columbia University, College of Physicians and Surgeons, and New York State Psychiatric Institute, New York; Department of Psychiatry, University of Pennsylvania, Philadelphia; University of Pittsburgh School of Medicine and Western Psychiatric Institute and Clinic, Pittsburgh; Department of Psychiatry, University of Rochester Medical Center, Rochester, N.Y.; and the Monash University Centre for Developmental Psychiatry and Psychology, Victoria, Australia.
Laurence Greenhill, M.D.
From the Department of Psychiatry and the Division of Child and Adolescent Psychiatry, Columbia University, College of Physicians and Surgeons, and New York State Psychiatric Institute, New York; Department of Psychiatry, University of Pennsylvania, Philadelphia; University of Pittsburgh School of Medicine and Western Psychiatric Institute and Clinic, Pittsburgh; Department of Psychiatry, University of Rochester Medical Center, Rochester, N.Y.; and the Monash University Centre for Developmental Psychiatry and Psychology, Victoria, Australia.
Sa Shen, Ph.D.
From the Department of Psychiatry and the Division of Child and Adolescent Psychiatry, Columbia University, College of Physicians and Surgeons, and New York State Psychiatric Institute, New York; Department of Psychiatry, University of Pennsylvania, Philadelphia; University of Pittsburgh School of Medicine and Western Psychiatric Institute and Clinic, Pittsburgh; Department of Psychiatry, University of Rochester Medical Center, Rochester, N.Y.; and the Monash University Centre for Developmental Psychiatry and Psychology, Victoria, Australia.
J. John Mann, M.D.
From the Department of Psychiatry and the Division of Child and Adolescent Psychiatry, Columbia University, College of Physicians and Surgeons, and New York State Psychiatric Institute, New York; Department of Psychiatry, University of Pennsylvania, Philadelphia; University of Pittsburgh School of Medicine and Western Psychiatric Institute and Clinic, Pittsburgh; Department of Psychiatry, University of Rochester Medical Center, Rochester, N.Y.; and the Monash University Centre for Developmental Psychiatry and Psychology, Victoria, Australia.

Notes

Address correspondence to Dr. Posner ([email protected]).

Funding Information

Dr. Posner receives royalty payments for the electronic self-rated versions of the Columbia–Suicide Severity Rating Scale (eC-SSRS) from ERT, Inc., and is the director of the Center for Suicide Risk Assessment, which, as part of an effort to help execute the U.S. Food and Drug Administration's suicidality classification mandates, has received support from Abbott, Albany Molecular Research, Alfresa, Alkermes, Amgen, AstraZeneca, Biodelivery Sciences International, Biomarin, Bristol-Myers Squibb, Canam, Cato Research, Cephalon, Cetero Research, Covance, CRI Worldwide, Depomed, Douglas Pharmaceuticals, Eisai, Euthymics, Forest, GlaxoSmithKline, GW Pharma, Human Genome Sciences, i3 Research, ICON, IntelGenx, Intracellular Therapies, Johnson & Johnson, Kendle Early Stage, Lilly USA, Lundbeck A/S, Lundbeck USA, MedImmune, Medtronic, Merck, Neurosearch, Next Wave Pharmaceuticals, Novartis, Noven, NovoNordisk, Orexigen, Otsuka, Parexel, Pfizer, PGx Health, Pharmaceutical Product Development, Inc., Psyadon, QED, Quintiles, Reckitt Benckiser, Roche, Sanofi-Aventis, Schering-Plough, SCOPE International, Sepracor/Sunovion, Shire, Siena Biotech, Supernus, Synosia Therapeutics, Takeda, Theravance, Upsher-Smith, Valeant, Vivus, World Wide Clinical Trials, and Wyeth Research. Dr. Brown receives royalty payments for eC-SSRS from ERT, Inc. Dr. Stanley receives royalty payments for eC-SSRS from ERT, Inc. Dr. Brent receives research support from NIMH, royalties from Guilford Press, and honoraria for serving on the editorial board of UpToDate and for CME presentations. Dr. Oquendo has received unrestricted educational grants or lecture fees from AstraZeneca, Bristol-Myers Squibb, Eli Lilly, Janssen, Otsuko, Pfizer, Sanofi-Aventis, and Shire, owns equity in Bristol-Myers Squibb, and receives royalty payments for eC-SSRS from ERT, Inc. Dr. Greenhill has received research support from Rhodes Pharmaceutical, National Institute on Drug Abuse, and Johnson & Johnson and study medication and placebo from Shire Pharmaceuticals for an investigator-initiated imaging study. Dr. Mann has received research support from GlaxoSmithKline and Novartis and receives royalty payments for eC-SSRS from ERT, Inc. The other authors report no financial relationships with commercial interests.The Treatment of Adolescent Suicide Attempters study (study 1 in the article) was funded by NIMH through cooperative agreement grants MH66750 (Duke University Medical Center), MH66769 (Johns Hopkins University), MH66762 (New York State Psychiatric Institute), MH66775 (University of Pittsburgh), and MH66778 (University of Texas Southwestern Medical Center). The adult emergency department study was funded in part by a grant from the American Foundation for Suicide Prevention to Drs. Brown, Currier, and Stanley and by a National Institute on Alcohol Abuse and Alcoholism “Developing Centers on Interventions for the Prevention of Suicide” grant (5 P20 AA015630) to Dr. Stanley. The data for the analysis of the escitalopram trial (study 2) were provided by Forest Laboratories, which did not participate in the data analysis, interpretation of results, or review or contribute to this article.

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