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Published Online: March 1950

STUDIES OF ADRENAL CORTICAL ACTIVITY IN PSYCHONEUROTIC SUBJECTS

R. A. CLEGHORN and B. F. GRAHAMAuthors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 106, Number 9

https://doi.org/10.1176/ajp.106.9.668

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Abstract

The use of a cumulative index of adrenal cortical activity has been described.

This has been applied to the estimation of adrenocortical activity after (1) small doses of ACTH in anxiety states, (2) injection of saline and venipuncture, (3) controlled thermal pain, and (4) electroconvulsive therapy.

In all these experiments the data indicate activation of the adrenal cortex.

It is suggested that the greater the patient's anxiety and tenseness the greater the activation of the adrenal cortex by the test situation.

The use of pretreatment sodium amytal seems to decrease the response of the adrenal cortex to ECT.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 106 • Number 9 • March 1950

Pages: 668 - 672

PubMed: 15410224

History

Published in print: March 1950

Published online: 1 April 2006

Authors

Details

R. A. CLEGHORN

The Department of Psychiatry, McGill University, and the Allan Memorial Institute of Psychiatry.

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B. F. GRAHAM

The Department of Psychiatry, McGill University, and the Allan Memorial Institute of Psychiatry.

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STUDIES OF ADRENAL CORTICAL ACTIVITY IN PSYCHONEUROTIC SUBJECTS

Abstract

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