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Published Online: July 1950

THE USE OF ANTABUSE (TETRAETHYLTHIURAMIDISULPHIDE) IN CHRONIC ALCOHOLICS

Publication: American Journal of Psychiatry

Abstract

1. Fourteen of 21 cases treated with Antabuse abstained from alcohol for periods of 2 to 4 months. Twenty-one cases represent too small a group from which to draw many general conclusions. However, the drug appears to have value in the treatment of chronic alcoholism but it has to be given under controlled conditions and in conjunction with psychotherapy. It appears to be more effective than other drug or conditioned reflex therapies used previously.
2. Further coordinate research including internal medical, pharmacologic, psychologic, and social service studies in conjunction with the psychiatric observations are indicated on a greater number of cases to establish the value of the drug. Furthermore, the patients should be studied over a longer period of time, i. e., about a year, to determine the permanency of their abstinence.
3. Under controlled conditions no severe untoward effects were noted.

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Published In

Go to American Journal of Psychiatry
Go to American Journal of Psychiatry
American Journal of Psychiatry
Pages: 8 - 13
PubMed: 15419328

History

Published in print: July 1950
Published online: 1 April 2006

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Details

S. EUGENE BARRERA
The Department of Neurology and Psychiatry, Albany Medical College and Hospital, and The Veterans Administration Mental Hygiene Clinic, Watervliet, N. Y.
WALTER A. OSINSKI
The Department of Neurology and Psychiatry, Albany Medical College and Hospital, and The Veterans Administration Mental Hygiene Clinic, Watervliet, N. Y.
EUGENE DAVIDOFF
The Department of Neurology and Psychiatry, Albany Medical College and Hospital, and The Veterans Administration Mental Hygiene Clinic, Watervliet, N. Y.

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