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Published Online: April 1962

COMBINED PSYCHOPHARMACEUTICAL TREATMENT IN 460 NEUROPSYCHIATRIC PATIENTS

Publication: American Journal of Psychiatry

Abstract

The combination of meprobamate, chlorpromazine, and nialamide appeared to effect the best results. Sixty-one percent of the group on these medicaments were greatly improved. Meprobamate, chlorpromazine, and tofrānil produced the next greatest improvement in 59%; meprobamate and chlorpromazine in 58%.
Side effects showed a decreased percentage in multiple medication. This can be partially accounted for by the fact that in the single medication group larger doses were required. The ameliorating effect of meprobamate on side reactions was also considered to be a factor in reducing the side effects by decreasing anxiety, bettering sleep and thereby reducing the amount of phenothiazines necessary for improvement.

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Go to American Journal of Psychiatry
Go to American Journal of Psychiatry
American Journal of Psychiatry
Pages: 935 - 937
PubMed: 14485130

History

Published in print: April 1962
Published online: 1 April 2006

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VERONICA M. PENNINGTON
Chief, Hospital Section of Psychiatry, VA Center, Jackson, Miss.

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