Marijuana and Amphetamine: The Question of Interaction

Animal studies have indicated that marijuana has both a depressive and an excitatory effect on the central nervous system. Since drug users occasionally combine marijuana and amphetamines, a study was performed to determine whether the two drugs have an interaction effect on a variety of physiologic and psychological measures. In general, no such interaction was demonstrated. Previously reported physiological effects of marijuana and amphetamines were confirmed, although some of the psychological effects were at variance with previously reported findings.