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Published Online: July 1939

ANOMALIES AND DANGERS IN THE METRAZOL THERAPY OF SCHIZOPHRENIA

LAWRENCE E. GEESLIN and HERVEY CLECKLEYAuthors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 96, Number 1

https://doi.org/10.1176/ajp.96.1.183

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Abstract

1. Various motor phenomena bearing little resemblance to the typical grand mal epileptic seizure or to the usual description of the seizure induced by metrazol occasionally occur.

2. The possible dangers from protracted tonic reactions secondary to the usual seizures should be kept in mind. The threat of persistent anoxia may under such circumstances become ominous.

3. When metrazol therapy is being used every available means should be at hand to combat such developments.

4. All anomalous reactions which suggest yet unrecognized complications of metrazol should be reported in detail. Warnings concerning the possibility of such dangers have already been sounded.⁴⁸ The practice of repeating the metrazol injection within a few minutes, though apparently safe in most cases, is not recommended.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 96 • Number 1 • July 1939

Pages: 183 - 191

History

Published in print: July 1939

Published online: 1 April 2006

Authors

Affiliations

LAWRENCE E. GEESLIN

The Departments of Internal Medicine and Psychiatry, The University of Georgia School of Medicine, Augusta, Ga.

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HERVEY CLECKLEY

The Departments of Internal Medicine and Psychiatry, The University of Georgia School of Medicine, Augusta, Ga.

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ANOMALIES AND DANGERS IN THE METRAZOL THERAPY OF SCHIZOPHRENIA

Abstract

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