METRAZOL AS A DIAGNOSTIC AID IN EPILEPSY

H. H. GOLDSTEIN and J. WEINBERGAuthors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 96, Number 6

https://doi.org/10.1176/ajp.96.6.1455

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Abstract

Differences of convulsive reactivity are manifested when a stimulating agent to the central nervous system is given to a group of individuals.

In 84 patients suffering from functional psychoses and with a standard dose of metrazol used as a stimulant, 1.19% developed a seizure. The one patient having a convulsion was quite possibly incorrectly diagnosed. Of 34 epileptic patients, 47.05 per cent developed seizures on a dose equal to that for schizophrenic and other patients.

Patients developing grand mal seizures with a dose of five cubic centimeters or less per 100-pound body weight (45. 5 kilograms) have an increased irritability of the nervous system and epilepsy is to be suspected in the absence of any evidence of organic disease of the brain.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 96 • Number 6 • May 1940

Pages: 1455 - 1458

History

Published in print: May 1940

Published online: 1 April 2006

Authors

Affiliations

H. H. GOLDSTEIN

The Chicago State Hospital.

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J. WEINBERG

The Chicago State Hospital.

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METRAZOL AS A DIAGNOSTIC AID IN EPILEPSY

Abstract

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