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Published Online: 16 January 2024

The Psychiatrist’s Role in Treating Perinatal Opioid Use Disorder and Reducing Maternal Mortality

Abstract

Drug overdose is a leading cause of maternal mortality. Psychiatrists can play a critical role in reducing these deaths by delivering effective evidence-based treatments for perinatal opioid use disorder (POUD), including the use of buprenorphine. Medications for POUD (i.e., buprenorphine, methadone) are life-saving treatments, but only half of those who are diagnosed as having POUD will receive this treatment, which can result in an increased risk for return to opioid use, overdose, and death. Psychiatrists are well positioned to prescribe buprenorphine given the Drug Enforcement Administration’s (DEA) removal of the requirement to submit a Notice of Intent to prescribe buprenorphine for the treatment of opioid use disorders. Psychiatrists who have a current DEA registration that includes Schedule III authority may now prescribe buprenorphine for opioid use disorders; the training requirements to do so are outlined herein. This article reviews the standard of care for screening, diagnosis, and treatment of POUD, and prescribing buprenorphine for POUD, as well as shared decision-making for medication selection, induction, and maintenance of buprenorphine during pregnancy, labor and delivery, and the postpartum year.

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Information & Authors

Information

Published In

History

Published in print: Winter 2024
Published online: 16 January 2024

Keywords

  1. Substance-Related and Addictive Disorders
  2. Opioids
  3. Pregnancy and Childbirth

Authors

Details

Sara M. Witcraft, Ph.D.
Department of Psychiatry and Behavioral Sciences (all authors) and Department of Obstetrics and Gynecology (Guille), Medical University of South Carolina, Charleston.
Claire Johnson, B.A.
Department of Psychiatry and Behavioral Sciences (all authors) and Department of Obstetrics and Gynecology (Guille), Medical University of South Carolina, Charleston.
Constance Guille, M.D., M.S.C.R. [email protected]
Department of Psychiatry and Behavioral Sciences (all authors) and Department of Obstetrics and Gynecology (Guille), Medical University of South Carolina, Charleston.

Notes

Send correspondence to Dr. Guille ([email protected]).

Competing Interests

Dr. Guille reports being a Visiting Scientist for and receiving consulting honorarium from Maven Clinic—an online women’s and family health platform. The other authors report no financial relationships with commercial interests.

Funding Information

Supported by NIDA grant K12 DA031794 (to Dr. Witcraft) and the Patient-Centered Outcomes Research Institute grant IHS-2021C3-24493 (to Dr. Guille). Additional support was received from NIDA and Office of Research on Women’s Health as part of a Specialized Center of Research Excellence on Sex Differences through grant U54DA016511 and NIDA Clinical Trials Network through grant UG1DA013727 (to Dr. Guille). None of the funding sources had a role in the preparation, review, or approval of the manuscript, or the decision to submit the manuscript for publication.

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