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Abstract

Objective:

Prolonged duration of untreated psychosis (DUP) predicts poor outcomes of first-episode psychosis (FEP) and is often linked to low socioeconomic status (SES). The authors sought to determine whether patients’ personal income, used as a proxy for SES, predicts length of DUP and whether personal income influences the effect of an early psychosis detection campaign—called Mindmap—on DUP reduction.

Methods:

Data were drawn from a trial that compared the effectiveness of early detection in reducing DUP across the catchment area of an FEP service (N=147 participants) compared with an FEP service with no early detection (N=75 participants). Hierarchical regression was used to determine whether personal income predicted DUP when analyses controlled for effects of age, race, and exposure to early psychosis detection. A group × personal income interaction term was used to assess whether the DUP difference between the early detection and control groups differed by personal income.

Results:

Lower personal income was significantly associated with younger age, fewer years of education, Black race, and longer DUP. Personal income predicted DUP beyond the effects of age, race, and early psychosis detection. Although Mindmap significantly reduced DUP across all income levels, this effect was smaller for participants reporting lower personal income.

Conclusions:

Patients’ personal income may be an important indicator of disparity in access to specialty care clinics across a wide range of settings. Early detection efforts should measure and target personal income and other SES indicators to improve access for all individuals who may benefit from FEP services.

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Supplementary Material

File (appi.ps.20230239.ds001.pdf)

Information & Authors

Information

Published In

Go to Psychiatric Services
Go to Psychiatric Services
Psychiatric Services
Pages: 427 - 433
PubMed: 38204369

History

Received: 24 May 2023
Revision received: 18 September 2023
Accepted: 16 October 2023
Published online: 11 January 2024
Published in print: May 01, 2024

Keywords

  1. Early intervention services
  2. First-episode psychosis
  3. Socioeconomic status
  4. Schizophrenia
  5. Social determinants of health
  6. Duration of untreated psychosis

Authors

Affiliations

Shruthi Venkataraman, M.D., M.Sc.
Department of Medicine, Faculty of Medicine and Health Sciences, McGill University, Montreal (Venkataraman); Department of Psychiatry, Program for Specialized Treatment Early in Psychosis, Yale University School of Medicine, New Haven (Hazan, Ferrara, Musket, Levine, Srihari); Yale Center for Analytical Sciences, Yale School of Public Health, New Haven (Li); Department of Neuroscience and Rehabilitation, University of Ferrara, Ferrara, Italy (Ferrara); Department of Psychiatry, McGill University, Montreal (Harper, Shah); Center for Brain Health, School of Brain and Behavioral Science, University of Texas at Dallas, Dallas (Ma); Department of Psychiatry, Veterans Affairs Connecticut Healthcare System, West Haven (Musket); Department of Psychiatry, Harvard Medical School at Beth Israel Deaconess Medical Center, Boston (Keshavan).
Hadar Hazan, Ph.D.
Department of Medicine, Faculty of Medicine and Health Sciences, McGill University, Montreal (Venkataraman); Department of Psychiatry, Program for Specialized Treatment Early in Psychosis, Yale University School of Medicine, New Haven (Hazan, Ferrara, Musket, Levine, Srihari); Yale Center for Analytical Sciences, Yale School of Public Health, New Haven (Li); Department of Neuroscience and Rehabilitation, University of Ferrara, Ferrara, Italy (Ferrara); Department of Psychiatry, McGill University, Montreal (Harper, Shah); Center for Brain Health, School of Brain and Behavioral Science, University of Texas at Dallas, Dallas (Ma); Department of Psychiatry, Veterans Affairs Connecticut Healthcare System, West Haven (Musket); Department of Psychiatry, Harvard Medical School at Beth Israel Deaconess Medical Center, Boston (Keshavan).
Fangyong Li, M.P.H.
Department of Medicine, Faculty of Medicine and Health Sciences, McGill University, Montreal (Venkataraman); Department of Psychiatry, Program for Specialized Treatment Early in Psychosis, Yale University School of Medicine, New Haven (Hazan, Ferrara, Musket, Levine, Srihari); Yale Center for Analytical Sciences, Yale School of Public Health, New Haven (Li); Department of Neuroscience and Rehabilitation, University of Ferrara, Ferrara, Italy (Ferrara); Department of Psychiatry, McGill University, Montreal (Harper, Shah); Center for Brain Health, School of Brain and Behavioral Science, University of Texas at Dallas, Dallas (Ma); Department of Psychiatry, Veterans Affairs Connecticut Healthcare System, West Haven (Musket); Department of Psychiatry, Harvard Medical School at Beth Israel Deaconess Medical Center, Boston (Keshavan).
Maria Ferrara, M.D., Ph.D.
Department of Medicine, Faculty of Medicine and Health Sciences, McGill University, Montreal (Venkataraman); Department of Psychiatry, Program for Specialized Treatment Early in Psychosis, Yale University School of Medicine, New Haven (Hazan, Ferrara, Musket, Levine, Srihari); Yale Center for Analytical Sciences, Yale School of Public Health, New Haven (Li); Department of Neuroscience and Rehabilitation, University of Ferrara, Ferrara, Italy (Ferrara); Department of Psychiatry, McGill University, Montreal (Harper, Shah); Center for Brain Health, School of Brain and Behavioral Science, University of Texas at Dallas, Dallas (Ma); Department of Psychiatry, Veterans Affairs Connecticut Healthcare System, West Haven (Musket); Department of Psychiatry, Harvard Medical School at Beth Israel Deaconess Medical Center, Boston (Keshavan).
Annie Harper, Ph.D.
Department of Medicine, Faculty of Medicine and Health Sciences, McGill University, Montreal (Venkataraman); Department of Psychiatry, Program for Specialized Treatment Early in Psychosis, Yale University School of Medicine, New Haven (Hazan, Ferrara, Musket, Levine, Srihari); Yale Center for Analytical Sciences, Yale School of Public Health, New Haven (Li); Department of Neuroscience and Rehabilitation, University of Ferrara, Ferrara, Italy (Ferrara); Department of Psychiatry, McGill University, Montreal (Harper, Shah); Center for Brain Health, School of Brain and Behavioral Science, University of Texas at Dallas, Dallas (Ma); Department of Psychiatry, Veterans Affairs Connecticut Healthcare System, West Haven (Musket); Department of Psychiatry, Harvard Medical School at Beth Israel Deaconess Medical Center, Boston (Keshavan).
Jessica Ma, B.S.
Department of Medicine, Faculty of Medicine and Health Sciences, McGill University, Montreal (Venkataraman); Department of Psychiatry, Program for Specialized Treatment Early in Psychosis, Yale University School of Medicine, New Haven (Hazan, Ferrara, Musket, Levine, Srihari); Yale Center for Analytical Sciences, Yale School of Public Health, New Haven (Li); Department of Neuroscience and Rehabilitation, University of Ferrara, Ferrara, Italy (Ferrara); Department of Psychiatry, McGill University, Montreal (Harper, Shah); Center for Brain Health, School of Brain and Behavioral Science, University of Texas at Dallas, Dallas (Ma); Department of Psychiatry, Veterans Affairs Connecticut Healthcare System, West Haven (Musket); Department of Psychiatry, Harvard Medical School at Beth Israel Deaconess Medical Center, Boston (Keshavan).
Jai Shah, M.D., F.R.C.P.C.
Department of Medicine, Faculty of Medicine and Health Sciences, McGill University, Montreal (Venkataraman); Department of Psychiatry, Program for Specialized Treatment Early in Psychosis, Yale University School of Medicine, New Haven (Hazan, Ferrara, Musket, Levine, Srihari); Yale Center for Analytical Sciences, Yale School of Public Health, New Haven (Li); Department of Neuroscience and Rehabilitation, University of Ferrara, Ferrara, Italy (Ferrara); Department of Psychiatry, McGill University, Montreal (Harper, Shah); Center for Brain Health, School of Brain and Behavioral Science, University of Texas at Dallas, Dallas (Ma); Department of Psychiatry, Veterans Affairs Connecticut Healthcare System, West Haven (Musket); Department of Psychiatry, Harvard Medical School at Beth Israel Deaconess Medical Center, Boston (Keshavan).
Christie Musket, Ph.D.
Department of Medicine, Faculty of Medicine and Health Sciences, McGill University, Montreal (Venkataraman); Department of Psychiatry, Program for Specialized Treatment Early in Psychosis, Yale University School of Medicine, New Haven (Hazan, Ferrara, Musket, Levine, Srihari); Yale Center for Analytical Sciences, Yale School of Public Health, New Haven (Li); Department of Neuroscience and Rehabilitation, University of Ferrara, Ferrara, Italy (Ferrara); Department of Psychiatry, McGill University, Montreal (Harper, Shah); Center for Brain Health, School of Brain and Behavioral Science, University of Texas at Dallas, Dallas (Ma); Department of Psychiatry, Veterans Affairs Connecticut Healthcare System, West Haven (Musket); Department of Psychiatry, Harvard Medical School at Beth Israel Deaconess Medical Center, Boston (Keshavan).
Nina Levine, M.P.H.
Department of Medicine, Faculty of Medicine and Health Sciences, McGill University, Montreal (Venkataraman); Department of Psychiatry, Program for Specialized Treatment Early in Psychosis, Yale University School of Medicine, New Haven (Hazan, Ferrara, Musket, Levine, Srihari); Yale Center for Analytical Sciences, Yale School of Public Health, New Haven (Li); Department of Neuroscience and Rehabilitation, University of Ferrara, Ferrara, Italy (Ferrara); Department of Psychiatry, McGill University, Montreal (Harper, Shah); Center for Brain Health, School of Brain and Behavioral Science, University of Texas at Dallas, Dallas (Ma); Department of Psychiatry, Veterans Affairs Connecticut Healthcare System, West Haven (Musket); Department of Psychiatry, Harvard Medical School at Beth Israel Deaconess Medical Center, Boston (Keshavan).
Matcheri S. Keshavan, M.D.
Department of Medicine, Faculty of Medicine and Health Sciences, McGill University, Montreal (Venkataraman); Department of Psychiatry, Program for Specialized Treatment Early in Psychosis, Yale University School of Medicine, New Haven (Hazan, Ferrara, Musket, Levine, Srihari); Yale Center for Analytical Sciences, Yale School of Public Health, New Haven (Li); Department of Neuroscience and Rehabilitation, University of Ferrara, Ferrara, Italy (Ferrara); Department of Psychiatry, McGill University, Montreal (Harper, Shah); Center for Brain Health, School of Brain and Behavioral Science, University of Texas at Dallas, Dallas (Ma); Department of Psychiatry, Veterans Affairs Connecticut Healthcare System, West Haven (Musket); Department of Psychiatry, Harvard Medical School at Beth Israel Deaconess Medical Center, Boston (Keshavan).
Vinod Srihari, M.D. [email protected]
Department of Medicine, Faculty of Medicine and Health Sciences, McGill University, Montreal (Venkataraman); Department of Psychiatry, Program for Specialized Treatment Early in Psychosis, Yale University School of Medicine, New Haven (Hazan, Ferrara, Musket, Levine, Srihari); Yale Center for Analytical Sciences, Yale School of Public Health, New Haven (Li); Department of Neuroscience and Rehabilitation, University of Ferrara, Ferrara, Italy (Ferrara); Department of Psychiatry, McGill University, Montreal (Harper, Shah); Center for Brain Health, School of Brain and Behavioral Science, University of Texas at Dallas, Dallas (Ma); Department of Psychiatry, Veterans Affairs Connecticut Healthcare System, West Haven (Musket); Department of Psychiatry, Harvard Medical School at Beth Israel Deaconess Medical Center, Boston (Keshavan).

Notes

Send correspondence to Dr. Srihari ([email protected]).

Competing Interests

Dr. Srihari reports being a cofounder of STEP-Forward, L.L.C., which provides consultation for services development and workforce development. The other authors report no financial relationships with commercial interests.

Funding Information

This work was supported by NIH (R01 MH103831 to Dr. Srihari) and by the State of Connecticut Department of Mental Health and Addiction Services.

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