Full access
Clinical & Research News
Published Online: 19 November 2004

Developing Drugs to Target Cognitive Deficits

Publication: Psychiatric News
Volume 39, Number 22
https://doi.org/10.1176/pn.39.22.00390037
Efforts are under way to attract drug company interest in developing medications to improve the cognitive functioning of patients with schizophrenia, the feature of the disease most strongly associated with functional outcome.
Stephen Marder, M.D., described several efforts in this area, including a program at the National Institute of Mental Health known as the Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS). These are the specific goals of MATRICS:
•
To catalyze regulatory acceptance of cognition in schizophrenia as a target for drug registration.
•
To promote development of novel compounds to enhance cognition in schizophrenia.
•
To leverage the drug industry's economic research power to focus on important but neglected clinical targets.
•
To identify lead compounds and, if deemed feasible, support human proof of concept trials for cognition in schizophrenia.
Marder also cited another NIMH-funded program called Treatment Units for Research on Neurocognition in Schizophrenia (TURNS). The TURNS program will provide an infrastructure for clinical studies of pharmacological agents for enhancing neurocognition in patients with schizophrenia.
Marder is the principal investigator in both of those programs. Information about them is posted online at<www.matrics.ucla.edu> and<www.turns.ucla.edu>.

Information & Authors

Information

Published In

Go to Psychiatric News
Psychiatric News
Volume 39 • Number 22 • November 19, 2004
Pages: 37

History

Published online: 19 November 2004
Published in print: November 19, 2004

Authors

Metrics & Citations

Metrics

Citations

Export Citations

If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click Download.

For more information or tips please see 'Downloading to a citation manager' in the Help menu.

Format
Citation style
Style
Copy to clipboard
Tips for downloading citations

There are no citations for this item

View Options

View options

Get Access

Login options

Already a subscriber? Access your subscription through your login credentials or your institution for full access to this article.

Personal login Institutional Login Open Athens login

Not a subscriber?

Subscribe Now / Learn More

PsychiatryOnline subscription options offer access to the DSM-5-TR® library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development.

Need more help? PsychiatryOnline Customer Service may be reached by emailing [email protected] or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.).

Media

Figures

Other

Tables

Share

Share

Share article link

Share

×

As described within the American Psychiatric Association (APA)'s Privacy Policy and Terms of Use, this website utilizes cookies, including for the purpose of offering an optimal online experience and services tailored to your preferences. Please read the entire Privacy Policy and Terms of Use. By closing this message, browsing this website, continuing the navigation, or otherwise continuing to use the APA's websites, you confirm that you understand and accept the terms of the Privacy Policy and Terms of Use, including the utilization of cookies.