Full access
Clinical & Research News
Published Online: 20 January 2006

Molecular Targets Ranked

Publication: Psychiatric News
Volume 41, Number 2
https://doi.org/10.1176/pn.41.2.0016a
Track CitationsAdd to favorites
PDF/EPUB
Scientists participating in the NIMH-sponsored MATRICS project ranked these molecular targets as the nine most promising targets for development of a drug to treat cognitive impairments in schizophrenia. The nine molecular targets are implicated in seven domains of cognition: working memory, attention/vigilance, verbal learning and memory, visual learning and memory, speed of processing, reasoning and problem-solving, and social cognition.
1. 
Alpha-7 nicotinic receptor agonists
2. 
D1 receptor agonists
3. 
AMPA glutamatergic receptor agonists
4. 
Alpha-2 adrenergic receptor agonists
5. 
NMDA glutamatergic receptor agonists
6. 
Metabotropic glutamate receptor agonists
7. 
Glycine reuptake inhibitors
8. 
M1 muscarinic receptor agonists
9. 
GABA-A receptor selective agonists

Information & Authors

Information

Published In

Go to Psychiatric News
Psychiatric News
Volume 41 • Number 2 • January 20, 2006
Pages: 16

History

Published online: 20 January 2006
Published in print: January 20, 2006

Authors

Metrics & Citations

Metrics

Citations

Export Citations

If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click Download.

For more information or tips please see 'Downloading to a citation manager' in the Help menu.

Format
Citation style
Style
Copy to clipboard
Tips for downloading citations

View Options

View options

PDF/EPUB

View PDF/EPUB

Login options

Already a subscriber? Access your subscription through your login credentials or your institution for full access to this article.

Personal login Institutional Login Open Athens login

Not a subscriber?

Subscribe Now / Learn More

PsychiatryOnline subscription options offer access to the DSM-5-TR® library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development.

Need more help? PsychiatryOnline Customer Service may be reached by emailing [email protected] or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.).

Media

Figures

Other

Tables

Share

Share

Share article link

Share

×

As described within the American Psychiatric Association (APA)'s Privacy Policy and Terms of Use, this website utilizes cookies, including for the purpose of offering an optimal online experience and services tailored to your preferences. Please read the entire Privacy Policy and Terms of Use. By closing this message, browsing this website, continuing the navigation, or otherwise continuing to use the APA's websites, you confirm that you understand and accept the terms of the Privacy Policy and Terms of Use, including the utilization of cookies.