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Published Online: August 1948

EARLY SENILE DEMENTIA IN MONGOLOID IDIOCY

Publication: American Journal of Psychiatry

Abstract

In 3 mongoloid patients aged respectively 47, 42, and 37 years, personality changes and mental deterioration were observed. Pathologically, evidence of senile changes was obtained consisting of degeneration of neurons, numerous senile plaques, and Alzheimer's neurofibrillary changes.
With the exception of the age of onset, the clinical and pathological manifestations are those of senile dementia.
Since mongoloid patients show a marked tendency to develop this type of reaction, it is suggested that the study of it offers some information which may contribute to a better understanding of the causes of senile dementia.

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Go to American Journal of Psychiatry
Go to American Journal of Psychiatry
American Journal of Psychiatry
Pages: 102 - 106
PubMed: 18876430

History

Published in print: August 1948
Published online: 1 April 2006

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GEORGE A. JERVIS
The Research Department, Letchworth Village, New York State Department of Mental Hygiene, Thiells, New York.

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