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Published Online: August 1948

PRESENILE PSYCHOSIS : Report of Two Cases with Brain Biopsy Studies

PHILLIP POLATIN, PAUL H. HOCH, WILLIAM A. HORWITZ, and LEON ROIZINAuthors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 105, Number 2

https://doi.org/10.1176/ajp.105.2.96

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Abstract

Two cases of Pick's disease are presented in which brain biopsy studies were made. The clinical, differential diagnostic, and neuropathological aspects of these cases are discussed.

This long neglected and poorly understood clinical entity—the presenile psychosis —is now receiving the close attention and careful scrutiny of more progressive neuropathologists and biochemists. The emphasis is no longer on changes in morphology but rather on the alterations occurring in the metabolism of brain tissue. With newer methods and finer techniques we can look forward to a better understanding of previously obscure neuropsychiatric disorders.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 105 • Number 2 • August 1948

Pages: 96 - 101

PubMed: 18876429

History

Published in print: August 1948

Published online: 1 April 2006

Authors

Affiliations

PHILLIP POLATIN

The Departments of Clinical Psychiatry and Neuropathology of the New York State Psychiatric Institute, 722 West 168th St., New York City.

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PAUL H. HOCH

The Departments of Clinical Psychiatry and Neuropathology of the New York State Psychiatric Institute, 722 West 168th St., New York City.

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WILLIAM A. HORWITZ

The Departments of Clinical Psychiatry and Neuropathology of the New York State Psychiatric Institute, 722 West 168th St., New York City.

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LEON ROIZIN

The Departments of Clinical Psychiatry and Neuropathology of the New York State Psychiatric Institute, 722 West 168th St., New York City.

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PRESENILE PSYCHOSIS : Report of Two Cases with Brain Biopsy Studies

Abstract

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