EXPERIMENTALLY PRODUCED PSYCHOSES

PAUL H. HOCHAuthors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 107, Number 8

https://doi.org/10.1176/ajp.107.8.607

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Abstract

Intravenous injection of synthetic mescaline was used in a group of schizophrenic patients and on "normal" voluntary controls. The changes produced by mescaline in "normals" were described. In addition, the observations were made that mescaline is able to underscore in patients suffering from schizophrenia their schizophrenic symptoms or able to precipitate schizophrenic psychoses in persons suffering from latent schizophrenia. Different "therapeutic measures" were discussed as applied to the mescaline-produced abnormal mental states.

Mescaline was also given to a number of patients before and after psychosurgery. It was found that with mescaline it was possible to reactivate the psychosis in patients who improved after psychosurgery but that their response to the drug was quantitatively less conspicuous than before.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 107 • Number 8 • February 1951

Pages: 607 - 611

PubMed: 14819349

History

Published in print: February 1951

Published online: 1 April 2006

Authors

Details

PAUL H. HOCH

The Department of Research Psychiatry, New York State Psychiatric Institute, New York City; College of Physicians and Surgeons, Columbia University, New York City.

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EXPERIMENTALLY PRODUCED PSYCHOSES

Abstract

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