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Published Online: March 1952

LIPOPROTEINS IN GENERAL AND CEREBRAL ARTERIOSCLEROSIS : Preliminary Report

ALEXANDER SIMON, JOHN W. GOFMAN, NATHAN MALAMUD, HARDIN B. JONES, and FRANK T. LINDGRENAuthors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 108, Number 9

https://doi.org/10.1176/ajp.108.9.663

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Abstract

1. Lipoprotein levels (S_t 10-20 class) of a group of patients diagnosed as psychosis with cerebral arteriosclerosis display little significant difference from a group of normals of similar age. If the level of lipoproteins (S_t 10-20 class) is a reflection of the activity of atheroma formation, then these patients show no more atherosclerotic activity than presumably normal individuals of the same age.

2. The autopsy findings in 24 cases suggest that cerebral atherosclerosis plays an insignificant role in so-called psychosis with cerebral arteriosclerosis, the latter being due either to senile or arteriolosclerotic changes. There appears to be a trend to more "lipoidosis" as observed in the aorta, coronary, and cerebral vessels, with increasing levels of S_t 10-20 lipoproteins in the blood serum.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 108 • Number 9 • March 1952

Pages: 663 - 668

PubMed: 14903194

History

Published in print: March 1952

Published online: 1 April 2006

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ALEXANDER SIMON

The Division of Psychiatry, University of California School of Medicine, San Francisco, the Division of Medical Physics, University of California, Berkeley, and The Langley Porter Clinic, Department of Mental Hygiene, State of California, San Francisco.

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JOHN W. GOFMAN

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NATHAN MALAMUD

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HARDIN B. JONES

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FRANK T. LINDGREN

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LIPOPROTEINS IN GENERAL AND CEREBRAL ARTERIOSCLEROSIS : Preliminary Report

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